Tacc2 transforming, acidic coiled-coil containing protein 2 [Rattus norvegicus (Norway rat)]
| Gene Symbol | Tacc2 |
| Entrez Gene ID | 309025 |
| Full Name | transforming, acidic coiled-coil containing protein 2 |
| Synonyms | |
| Gene Type | protein-coding |
| Organism | Rattus norvegicus (Norway rat) |
| Genome |
1 1q37 |
| Summary | This gene encodes a member of the transforming, acidic coiled-coil (TACC) family of proteins. Members of this family are centrosomal proteins that interact with microtubules and tubulin. TACC proteins are thought to be involved in centrosome/mitotic spindle dynamics and gene regulation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]. |
| Disorder | MIM: |
| mRNA | NM_001004415, 52486809 |
| Protein | NP_001004415, 52486810 |
| Product | transforming acidic coiled coil 2 isoform 1 |
| RefSeq Status | REVIEWED |
| mRNA | NM_001004418, 52486827 |
| Protein | NP_001004418, 52486828 |
| Product | transforming acidic coiled coil 2 isoform 2 |
| RefSeq Status | REVIEWED |
| Homo sapiens (human) | TACC2 | NP_996744.2 |
| Pan troglodytes (chimpanzee) | TACC2 | XP_001158836.1 |
| Canis lupus familiaris (dog) | TACC2 | XP_535042.2 |
| Bos taurus (cattle) | TACC2 | NP_001095629.1 |
| Mus musculus (house mouse) | Tacc2 | NP_001004468.1 |
| Rattus norvegicus (Norway rat) | Tacc2 | NP_001004415.1 |
| Gallus gallus (chicken) | TACC2 | XP_421798.2 |
| ID | Name | Evidence |
| GO:0000226 | microtubule cytoskeleton organization | ISO |
| GO:0008283 | cell proliferation | ISO |
| GO:0021987 | cerebral cortex development | ISO |
| GO:0022008 | neurogenesis | ISO |
| GO:0022027 | interkinetic nuclear migration | ISO |
| GO:0030953 | spindle astral microtubule organization | ISO |
| GO:0032886 | regulation of microtubule-based process | ISO |
Function
| ID | Name | Evidence |
| GO:0019904 | protein domain specific binding | ISO |
| GO:0035257 | nuclear hormone receptor binding | ISO |
| GeneCards | Tacc2 |
| UniProt | D4A858, D3ZXK3 |
| RGD | 1303004 |
| Ensembl | ENSRNOG00000020457 |
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