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HSPA1A heat shock 70kDa protein 1A [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_005345 Homo sapiens heat shock 70kDa protein 1A (HSPA1A), mRNA. GenEZ ORF Cloning In-stock $639.00 $590.00 15

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Gene Symbol HSPA1A
Entrez Gene ID 3303
Full Name heat shock 70kDa protein 1A
Synonyms FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1B
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p21.3

Summary This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008].
Disorder

MIM: 140550

mRNA Protein Product Sequence Price Select
NM_005345, 194248071 NP_005336, 194248072 heat shock 70 kDa protein 1A/1B ORF Sequence $490.00
KEGG
hsa04141Protein processing in endoplasmic reticulum
hsa05020Prion diseases
hsa04144Endocytosis
hsa05145Toxoplasmosis
hsa_M00353Spliceosome, Prp19/CDC5L complex
hsa05169Epstein-Barr virus infection
hsa03040Spliceosome
hsa05134Legionellosis
hsa04612Antigen processing and presentation
hsa05164Influenza A
hsa04010MAPK signaling pathway
hsa05162Measles
hsa_M00355Spliceosome, 35S U5-snRNP
Pathway Interaction Database
foxm1pathwayFOXM1 transcription factor network
p53downstreampathwayDirect p53 effectors
WikiPathways
WP384Apoptosis Modulation by HSP70
WP382MAPK signaling pathway
WP2359Parkin-Ubiquitin Proteasomal System pathway
Homo sapiens (human)HSPA1ANP_005336.3
Homo sapiens (human)HSPA1BNP_005337.2
Pan troglodytes (chimpanzee)HSPA1AXP_003311223.1
Macaca mulatta (Rhesus monkey)HSPA1BXP_001115060.2
Canis lupus familiaris (dog)HSP70NP_001003067.1
Bos taurus (cattle)HSPA1ANP_976067.2
Mus musculus (house mouse)Hspa1bNP_034608.2
Mus musculus (house mouse)Hspa1aNP_034609.2
Rattus norvegicus (Norway rat)Hspa1bNP_997669.1
Rattus norvegicus (Norway rat)Hspa1aNP_114177.2
Danio rerio (zebrafish)LOC100535101XP_003198158.1
Danio rerio (zebrafish)LOC798846NP_001093532.1
Danio rerio (zebrafish)zgc:174006NP_001120990.1
Danio rerio (zebrafish)hsp70lNP_001107061.1
Danio rerio (zebrafish)hsp70NP_571472.1
Drosophila melanogaster (fruit fly)Hsp70AbNP_524798.2
Drosophila melanogaster (fruit fly)Hsp68NP_524474.1
Drosophila melanogaster (fruit fly)Hsp70AaNP_731651.1
Drosophila melanogaster (fruit fly)Hsp70BcNP_650209.1
Drosophila melanogaster (fruit fly)Hsp70BaNP_731716.1
Drosophila melanogaster (fruit fly)Hsp70BbNP_524927.2
Drosophila melanogaster (fruit fly)Hsp70BbbNP_788663.1
Arabidopsis thaliana (thale cress)AT3G09440NP_001189847.1
GeneCards HSPA1A
UniProt B3KTT5
MIM 140550
Ensembl ENSG00000204389
HGNC 5232
HPRD 00774

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
heat shock 70 kDa protein 1A/1B
Names
heat shock 70 kDa protein 1A/1B
HSP70-1/HSP70-2
HSP70.1/HSP70.2
heat shock 70kD protein 1A
heat shock-induced protein
heat shock 70 kDa protein 1/2
dnaK-type molecular chaperone HSP70-1

Interactant



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