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COL2A1 collagen, type II, alpha 1 [Bos taurus (cattle)]

Summary
mRNA and Protein
Pathway
Homologues
Gene Ontology
Links to Other Databases

Gene Symbol	COL2A1
Entrez Gene ID	407142
Full Name	collagen, type II, alpha 1
Synonyms	CB11
Gene Type	protein-coding
Organism	Bos taurus (cattle)
Genome	Chromosome:5
Summary
Disorder	MIM:

mRNA	NM_001113224, 164414426
Protein	NP_001106695, 164414427
Product	collagen alpha-1(II) chain isoform 2
RefSeq Status	VALIDATED
mRNA	NM_001001135, 164414424
Protein	NP_001001135, 164414425
Product	collagen alpha-1(II) chain isoform 1
RefSeq Status	VALIDATED

KEGG

bta04510	Focal adhesion
bta04512	ECM-receptor interaction
bta05146	Amoebiasis
bta04974	Protein digestion and absorption

Reactome

1163781	Axon guidance
1163780	NCAM signaling for neurite out-growth
1164280	NCAM1 interactions
1163886	Integrin cell surface interactions
1163778	Signaling by PDGF

Process

ID	Name	Evidence
GO:0001502	cartilage condensation	IEA
GO:0001894	tissue homeostasis	IEA
GO:0001958	endochondral ossification	IEA
GO:0002062	chondrocyte differentiation	IEA
GO:0003007	heart morphogenesis	IEA
GO:0006029	proteoglycan metabolic process	IEA
GO:0007601	visual perception	IEA
GO:0007605	sensory perception of sound	IEA
GO:0010468	regulation of gene expression	IEA
GO:0030199	collagen fibril organization	IEA
GO:0035108	limb morphogenesis	IEA
GO:0042472	inner ear morphogenesis	IEA
GO:0043066	negative regulation of apoptosis	IEA
GO:0060021	palate development	IEA
GO:0060272	embryonic skeletal joint morphogenesis	IEA
GO:0060348	bone development	IEA
GO:0060351	cartilage development involved in endochondral bone morphogenesis	IEA

Component

ID	Name	Evidence
GO:0005576	extracellular region	IEA
GO:0005581	collagen	IEA
GO:0005585	collagen type II	IEA
GO:0005604	basement membrane	IEA
GO:0005615	extracellular space	IEA
GO:0005737	cytoplasm	IEA
GO:0031012	extracellular matrix	IEA

Function

ID	Name	Evidence
GO:0005201	extracellular matrix structural constituent	IEA
GO:0048407	platelet-derived growth factor binding	IEA

GeneCards	COL2A1
UniProt	P02459

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