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MAF v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001031804 Homo sapiens v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) (MAF), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_005360 Homo sapiens v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) (MAF), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Related Services

Gene Symbol MAF
Entrez Gene ID 4094
Full Name v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
Synonyms MGC71685, c-MAF
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010].

MIM: 177075

Cataract, pulverulent or cerulean, with or without microcornea (3)

mRNA Protein Product Sequence Price Select
NM_001031804, 197313769 NP_001026974, 73427806 transcription factor Maf isoform b ORF Sequence $400.00
NM_005360, 197313768 NP_005351, 5453736 transcription factor Maf isoform a ORF Sequence $400.00
hsa05202Transcriptional misregulation in cancer
WP3Keap1-Nrf2 Pathway
Pathway Interaction Database
cmyb_pathwayC-MYB transcription factor network
nfat_tfpathwayCalcineurin-regulated NFAT-dependent transcription in lymphocytes
Homo sapiens (human)MAFNP_005351.2
Pan troglodytes (chimpanzee)MAFXP_511123.2
Bos taurus (cattle)MAFNP_001099107.1
Mus musculus (house mouse)MafNP_001020748.2
Rattus norvegicus (Norway rat)MafNP_062191.1
Gallus gallus (chicken)MAFNP_001038136.1
Danio rerio (zebrafish)LOC100537332XP_003201520.1
Danio rerio (zebrafish)mafNP_571919.1
GeneCards MAF
UniProt O75444
MIM 177075
Ensembl ENSG00000178573
HGNC 6776
HPRD 01518

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
transcription factor Maf
transcription factor Maf
c-maf proto-oncogene
proto-oncogene c-Maf
T lymphocyte c-maf long form
Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene


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