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MAGOH mago-nashi homolog, proliferation-associated (Drosophila) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_002370 Homo sapiens mago-nashi homolog, proliferation-associated (Drosophila) (MAGOH), mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10

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Gene Symbol MAGOH
Entrez Gene ID 4116
Full Name mago-nashi homolog, proliferation-associated (Drosophila)
Synonyms MAGOH1, MAGOHA
General protein information
Preferred Names
protein mago nashi homolog
Names
protein mago nashi homolog
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p32.3

Summary Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602603

mRNA Protein Product Sequence Price Select
NM_002370, 320202965 NP_002361, 4505087 protein mago nashi homolog ORF Sequence $99.00
KEGG
hsa03040Spliceosome
hsa03013RNA transport
hsa03015mRNA surveillance pathway
hsa_M00430Exon junction complex (EJC)
Reactome
REACT_71Gene Expression
REACT_1281Transport of Mature Transcript to Cytoplasm
REACT_1597Transport of Mature mRNA derived from an Intron-Containing Transcript
REACT_467mRNA Splicing - Major Pathway
REACT_1849mRNA 3'-end processing
REACT_1735mRNA Splicing
REACT_1366RNA Polymerase II Transcription
REACT_894RNA Polymerase II Transcription Termination
REACT_387Cleavage of Growing Transcript in the Termination Region
REACT_125Processing of Capped Intron-Containing Pre-mRNA
REACT_75886Nonsense-Mediated Decay (NMD)
REACT_75822Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Homo sapiens (human)MAGOHNP_002361.1
Pan troglodytes (chimpanzee)LOC100613301XP_003308156.1
Macaca mulatta (Rhesus monkey)MAGOHXP_001112786.1
Canis lupus familiaris (dog)MAGOHXP_536702.1
Bos taurus (cattle)MAGOHNP_001029417.1
Mus musculus (house mouse)MagohNP_001269666.1
Rattus norvegicus (Norway rat)MagohNP_001094006.1
Gallus gallus (chicken)MAGOH2NP_989656.1
Process
IDNameEvidence
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decayIMP
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTAS
GO:0000381regulation of alternative mRNA splicing, via spliceosomeIMP
GO:0000398mRNA splicing, via spliceosomeIC
GO:0000398mRNA splicing, via spliceosomeTAS
GO:0006366transcription from RNA polymerase II promoterTAS
GO:0006369termination of RNA polymerase II transcriptionTAS
GO:0006406mRNA export from nucleusTAS
GO:0006417regulation of translationIEA
GO:0008380RNA splicingTAS
GO:0010467gene expressionTAS
GO:0016070RNA metabolic processTAS
GO:0016071mRNA metabolic processTAS
GO:0031124mRNA 3'-end processingTAS
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005654nucleoplasmTAS
GO:0005829cytosolTAS
GO:0016607nuclear speckIEA
GO:0035145exon-exon junction complexIDA
GO:0071013catalytic step 2 spliceosomeIDA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GO:0044822poly(A) RNA bindingIDA
GeneCards MAGOH
PDB 2XB2, 2J0S, 1P27, 2J0Q, 3EX7, 2HYI
UniProt P61326
Vega OTTHUMG00000008932
MIM 602603
Ensembl ENSG00000162385
HGNC 6815
HPRD 04005

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