Sequence in raw or FASTA format:
COL3A1 collagen, type III, alpha 1 [Bos taurus (cattle)]
|Entrez Gene ID||510833|
|Full Name||collagen, type III, alpha 1|
|General protein information||
|Organism||Bos taurus (cattle)|
|bta04974||Protein digestion and absorption|
|bta04151||PI3K-Akt signaling pathway|
|WP1040||Inflammatory Response Pathway|
|5494749||Scavenging by Class A Receptors|
|5494746||Binding and Uptake of Ligands by Scavenger Receptors|
|GO:0021987||cerebral cortex development||ISS|
|GO:0035025||positive regulation of Rho protein signal transduction||ISS|
|GO:2001223||negative regulation of neuron migration||ISS|
|GO:0005578||proteinaceous extracellular matrix||IEA|
What is the normal function of the COL3A1 gene?
The COL3A1 gene provides instructions for making a component of collagen. Collagens form a family of proteins that strengthen and support many tissues in the body. Type III collagen is found in tissues such as the skin, lungs, intestinal walls, and the walls of blood vessels. The COL3A1 gene produces the components of type III collagen, called pro-alpha1(III) chains. Three copies of this chain combine to make a molecule of type III procollagen. These triple-stranded, rope-like procollagen molecules must be processed by enzymes outside the cell to remove extra protein segments from their ends. Once these molecules are processed, the collagen molecules arrange themselves into long, thin fibrils. Within these fibrils, the individual collagen molecules are cross-linked to one another. These cross-links result in the formation of very strong mature type III collagen fibrils, which are found in the spaces around cells.
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