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COL3A1 collagen, type III, alpha 1 [Bos taurus (cattle)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001076831 Bos taurus collagen, type III, alpha 1 (COL3A1), mRNA. GenEZ ORF Cloning On-demand $1699.00 25

*Business Day

Related Services

Gene Symbol COL3A1
Entrez Gene ID 510833
Full Name collagen, type III, alpha 1
Synonyms
General protein information
Preferred Names
collagen alpha-1(III) chain
Names
collagen alpha-1(III) chain
collagen, type III, alpha 1 chain, fibril forming
collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)
Gene Type protein-coding
Organism Bos taurus (cattle)
Genome

2

2q12

Summary
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_001076831, 116003880 NP_001070299, 116003881 collagen alpha-1(III) chain precursor ORF Sequence $1500.00
KEGG
bta04510Focal adhesion
bta04512ECM-receptor interaction
bta05146Amoebiasis
bta04974Protein digestion and absorption
bta04151PI3K-Akt signaling pathway
bta04611Platelet activation
WikiPathways
WP1040Inflammatory Response Pathway
Reactome
5494749Scavenging by Class A Receptors
5494746Binding and Uptake of Ligands by Scavenger Receptors
Process
IDNameEvidence
GO:0021987cerebral cortex developmentISS
GO:0035025positive regulation of Rho protein signal transductionISS
GO:2001223negative regulation of neuron migrationISS
Component
IDNameEvidence
GO:0005576extracellular regionTAS
GO:0005578proteinaceous extracellular matrixIEA
GO:0005581collagen trimerIEA
GeneCards COL3A1
UniProt Q08E14
BGD BT10832
Ensembl ENSBTAG00000021466

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the COL3A1 gene?

The COL3A1 gene provides instructions for making a component of collagen. Collagens form a family of proteins that strengthen and support many tissues in the body. Type III collagen is found in tissues such as the skin, lungs, intestinal walls, and the walls of blood vessels. The COL3A1 gene produces the components of type III collagen, called pro-alpha1(III) chains. Three copies of this chain combine to make a molecule of type III procollagen. These triple-stranded, rope-like procollagen molecules must be processed by enzymes outside the cell to remove extra protein segments from their ends. Once these molecules are processed, the collagen molecules arrange themselves into long, thin fibrils. Within these fibrils, the individual collagen molecules are cross-linked to one another. These cross-links result in the formation of very strong mature type III collagen fibrils, which are found in the spaces around cells.

Interactant

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