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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


NME8 NME/NM23 family member 8 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu27090 NM_016616 Homo sapiens NME/NM23 family member 8 (NME8), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu27090C NM_016616 Homo sapiens NME/NM23 family member 8 (NME8), mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol NME8
Entrez Gene ID 51314
Full Name NME/NM23 family member 8
Synonyms CILD6, NM23-H8, SPTRX2, TXNDC3, sptrx-2
General protein information
Preferred Names
thioredoxin domain-containing protein 3
Names
thioredoxin domain-containing protein 3
sperm-specific thioredoxin 2
spermatid-specific thioredoxin-2
thioredoxin domain containing 3 (spermatozoa)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7p14.1

Summary This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009].
Disorder

MIM: 607421

Ciliary dyskinesia, primary, 6, 610852 (3)

mRNA Protein Product Sequence Price Select
NM_016616, 254911059 NP_057700, 148839372 thioredoxin domain-containing protein 3 ORF Sequence $700.00
Homo sapiens (human)NME8NP_057700.3
Pan troglodytes (chimpanzee)TXNDC3XP_527723.3
Macaca mulatta (Rhesus monkey)TXNDC3XP_001101594.1
Canis lupus familiaris (dog)NME8XP_851794.1
Mus musculus (house mouse)Nme8NP_853622.2
Rattus norvegicus (Norway rat)Nme8NP_942087.2
Gallus gallus (chicken)TXNDC3XP_426021.3
Danio rerio (zebrafish)nme8NP_001082944.1
Xenopus (Silurana) tropicalis (western clawed frog)nme9NP_001121456.1
Process
IDNameEvidence
GO:0006165nucleoside diphosphate phosphorylationIEA
GO:0006183GTP biosynthetic processIEA
GO:0006228UTP biosynthetic processIEA
GO:0006241CTP biosynthetic processIEA
GO:0007275multicellular organismal developmentIEA
GO:0007283spermatogenesisIEA
GO:0030154cell differentiationIEA
GO:0045454cell redox homeostasisIEA
Component
IDNameEvidence
GO:0005737cytoplasmIEA
Function
IDNameEvidence
GO:0004550nucleoside diphosphate kinase activityIEA
GO:0005524ATP bindingIEA
GeneCards NME8
UniProt Q8N427
Vega OTTHUMG00000023716
MIM 607421
Ensembl ENSG00000086288
HGNC 16473
HPRD 16243

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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