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ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu21926 NM_001688 Homo sapiens ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 (ATP5F1), mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu33497 XM_005270929 PREDICTED: Homo sapiens ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 (ATP5F1), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu21926C NM_001688 Homo sapiens ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 (ATP5F1), mRNA. Customized vector On-demand 7-9 $209.00
OHu33497C XM_005270929 PREDICTED: Homo sapiens ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 (ATP5F1), transcript variant X1, mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol ATP5F1
Entrez Gene ID 515
Full Name ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
Synonyms PIG47
General protein information
Preferred Names
ATP synthase subunit b, mitochondrial
Names
ATP synthase subunit b, mitochondrial
ATPase subunit b
H+-ATP synthase subunit b
ATP synthase B chain, mitochondrial
cell proliferation-inducing protein 47
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1
NP_001679.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p13.2

Summary This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the b subunit of the proton channel. [provided by RefSeq, Jul 2008].
Disorder

MIM: 603270

mRNA Protein Product Sequence Price Select
NM_001688, 85794838 NP_001679, 21361565 ATP synthase F(0) complex subunit B1, mitochondrial precursor ORF Sequence $300.00
XM_005270929, 530362758 XP_005270986, 530362759 ATP synthase F(0) complex subunit B1, mitochondrial isoform X1 ORF Sequence $400.00
KEGG
hsa00190Oxidative phosphorylation
hsa05016Huntington's disease
hsa05012Parkinson's disease
hsa05010Alzheimer's disease
hsa_M00158F-type ATPase, eukaryotes
WikiPathways
WP111Electron Transport Chain
WP623Oxidative phosphorylation
Reactome
REACT_6305Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
REACT_6759Formation of ATP by chemiosmotic coupling
REACT_111217Metabolism
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
Homo sapiens (human)ATP5F1NP_001679.2
Pan troglodytes (chimpanzee)ATP5F1XP_513639.1
Macaca mulatta (Rhesus monkey)ATP5F1XP_001105535.1
Canis lupus familiaris (dog)LOC479901XP_537027.2
Bos taurus (cattle)ATP5F1NP_001033590.1
Mus musculus (house mouse)Atp5f1NP_033855.2
Rattus norvegicus (Norway rat)Atp5f1NP_599192.1
Rattus norvegicus (Norway rat)LOC100911417XP_003749420.1
Gallus gallus (chicken)ATP5F1XP_417993.3
Danio rerio (zebrafish)atp5f1NP_001005960.1
Drosophila melanogaster (fruit fly)ATPsyn-bNP_524011.1
Xenopus (Silurana) tropicalis (western clawed frog)atp5f1NP_989118.1
Process
IDNameEvidence
GO:0006200ATP catabolic processIDA
GO:0015986ATP synthesis coupled proton transportIBA
GO:0021762substantia nigra developmentIEP
GO:0022904respiratory electron transport chainTAS
GO:0042776mitochondrial ATP synthesis coupled proton transportIC
GO:0042776mitochondrial ATP synthesis coupled proton transportTAS
GO:0044237cellular metabolic processTAS
GO:0044281small molecule metabolic processTAS
Component
IDNameEvidence
GO:0000276mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)IBA
GO:0005634nucleusIDA
GO:0005739mitochondrionIDA
GO:0005743mitochondrial inner membraneTAS
GO:0005753mitochondrial proton-transporting ATP synthase complexIDA
GO:0005759mitochondrial matrixNAS
GO:0016020membraneIDA
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GO:0016887ATPase activityIDA
GO:0022857transmembrane transporter activityIC
GO:0046933proton-transporting ATP synthase activity, rotational mechanismIBA
GeneCards ATP5F1
UniProt P24539, Q08ET0
MIM 603270
HGNC 840
HPRD 04467

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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