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PLCB2 phospholipase C, beta 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001284297 Homo sapiens phospholipase C, beta 2 (PLCB2), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_001284298 Homo sapiens phospholipase C, beta 2 (PLCB2), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_001284299 Homo sapiens phospholipase C, beta 2 (PLCB2), transcript variant 4, mRNA. GenEZ ORF Cloning On-demand $399.00 14
NM_004573 Homo sapiens phospholipase C, beta 2 (PLCB2), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand TBD TBD
XM_005254448 PREDICTED: Homo sapiens phospholipase C, beta 2 (PLCB2), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand TBD TBD
XM_005254449 PREDICTED: Homo sapiens phospholipase C, beta 2 (PLCB2), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand TBD TBD
XM_005254450 PREDICTED: Homo sapiens phospholipase C, beta 2 (PLCB2), transcript variant X5, mRNA. GenEZ ORF Cloning On-demand TBD TBD
XM_006720571 PREDICTED: Homo sapiens phospholipase C, beta 2 (PLCB2), transcript variant X7, mRNA. GenEZ ORF Cloning On-demand TBD TBD
XM_006720572 PREDICTED: Homo sapiens phospholipase C, beta 2 (PLCB2), transcript variant X8, mRNA. GenEZ ORF Cloning On-demand TBD TBD

*Business Day

Related Services

Gene Symbol PLCB2
Entrez Gene ID 5330
Full Name phospholipase C, beta 2
Synonyms PLC-beta-2
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q15

Summary
Disorder

MIM: 604114

Platelet PLC beta-2 deficiency (1)

mRNA Protein Product Sequence Price Select
NM_001284297, 546231594 NP_001271226, 546231595 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform 2 ORF Sequence $1500.00
NM_001284298, 546232004 NP_001271227, 546232005 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform 3 ORF Sequence $1500.00
NM_001284299, 546231498 NP_001271228, 546231499 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform 4 ORF Sequence $250.00
NM_004573, 95147332 NP_004564, 95147333 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform 1 ORF Sequence $1500.00
XM_005254448, 530405984 XP_005254505, 530405985 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X3 ORF Sequence $1500.00
XM_005254449, 530405986 XP_005254506, 530405987 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X4 ORF Sequence $1500.00
XM_005254450, 530405988 XP_005254507, 530405989 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X5 ORF Sequence $1500.00
XM_006720571, 578827089 XP_006720634, 578827090 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X7 ORF Sequence $1500.00
XM_006720572, 578827091 XP_006720635, 578827092 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X8 ORF Sequence $1500.00
KEGG
hsa00562Inositol phosphate metabolism
hsa04020Calcium signaling pathway
hsa04310Wnt signaling pathway
hsa04070Phosphatidylinositol signaling system
hsa04720Long-term potentiation
hsa04730Long-term depression
hsa04742Taste transduction
hsa04916Melanogenesis
hsa04912GnRH signaling pathway
hsa05016Huntington's disease
hsa04540Gap junction
hsa05010Alzheimer's disease
hsa04062Chemokine signaling pathway
hsa04270Vascular smooth muscle contraction
hsa05142Chagas disease (American trypanosomiasis)
hsa05146Amoebiasis
hsa04973Carbohydrate digestion and absorption
hsa04970Salivary secretion
hsa04971Gastric acid secretion
hsa04972Pancreatic secretion
hsa05143African trypanosomiasis
hsa04961Endocrine and other factor-regulated calcium reabsorption
hsa04724Glutamatergic synapse
hsa04725Cholinergic synapse
hsa_M00130Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
hsa04728Dopaminergic synapse
hsa04726Serotonergic synapse
hsa04723Retrograde endocannabinoid signaling
hsa04713Circadian entrainment
hsa04915Estrogen signaling pathway
hsa04918Thyroid hormone synthesis
hsa04261Adrenergic signaling in cardiomyocytes
hsa04911Insulin secretion
hsa04919Thyroid hormone signaling pathway
hsa04750Inflammatory mediator regulation of TRP channels
hsa04921Oxytocin signaling pathway
hsa04611Platelet activation
hsa04015Rap1 signaling pathway
hsa04022cGMP-PKG signaling pathway
WikiPathways
WP1544MicroRNAs in cardiomyocyte hypertrophy
WP26Signal Transduction of S1P Receptor
WP2059Alzheimers Disease
Pathway Interaction Database
alphasynuclein_pathwayAlpha-synuclein signaling
cxcr4_pathwayCXCR4-mediated signaling events
s1p_s1p1_pathwayS1P1 pathway
endothelinpathwayEndothelins
er_nongenomic_pathwayPlasma membrane estrogen receptor signaling
txa2pathwayThromboxane A2 receptor signaling
rac1_pathwayRAC1 signaling pathway
BIOCYC
HUMAN_LIPASYN-PWYphospholipases
HUMAN_PWY-6367D-myo-inositol-5-phosphate metabolism
HUMAN_PWY-6351D-myo-inositol (1,4,5)-trisphosphate biosynthesis
HUMAN_PWY-6371superpathway of inositol phosphate compounds
Reactome
REACT_19193Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
REACT_19184GPCR downstream signaling
REACT_19145G beta:gamma signalling through PLC beta
REACT_19375Free fatty acids regulate insulin secretion
REACT_19388G-protein beta:gamma signalling
REACT_18325Regulation of insulin secretion
REACT_18405Acetylcholine regulates insulin secretion
REACT_18283G alpha (q) signalling events
REACT_1505Integration of energy metabolism
REACT_14797Signaling by GPCR
REACT_15295Opioid Signalling
REACT_15526G-protein mediated events
REACT_15426PLC beta mediated events
REACT_11045Signaling by Wnt
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_13477Transmission across Chemical Synapses
REACT_13685Neuronal System
REACT_21312Activation of Kainate Receptors upon glutamate binding
REACT_21254Presynaptic function of Kainate receptors
REACT_111217Metabolism
REACT_111102Signal Transduction
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_150154Inositol phosphate metabolism
REACT_150312Synthesis of IP3 and IP4 in the cytosol
REACT_172761Ca2+ pathway
REACT_172694beta-catenin independent WNT signaling
Homo sapiens (human)PLCB2NP_001271227.1
Pan troglodytes (chimpanzee)PLCB2XP_510305.4
Macaca mulatta (Rhesus monkey)PLCB2XP_001095135.2
Canis lupus familiaris (dog)PLCB2XP_003640081.1
Bos taurus (cattle)PLCB2NP_001178330.1
Mus musculus (house mouse)Plcb2NP_808236.2
Rattus norvegicus (Norway rat)Plcb2NP_445930.1
Gallus gallus (chicken)PLCB2XP_420945.3
Xenopus (Silurana) tropicalis (western clawed frog)plcb2XP_004917351.1
Process
IDNameEvidence
GO:0006644phospholipid metabolic processTAS
GO:0007202activation of phospholipase C activityTAS
GO:0007268synaptic transmissionTAS
GO:0016042lipid catabolic processIEA
GO:0035556intracellular signal transductionIEA
GO:0043647inositol phosphate metabolic processTAS
GO:0044281small molecule metabolic processTAS
GO:0050913sensory perception of bitter tasteIEA
Component
IDNameEvidence
GO:0005829cytosolTAS
Function
IDNameEvidence
GO:0004435phosphatidylinositol phospholipase C activityIEA
GO:0004629phospholipase C activityTAS
GO:0004871signal transducer activityIEA
GO:0005509calcium ion bindingIEA
GeneCards PLCB2
PDB 2ZKM
UniProt Q59F77, Q00722, Q9BVT6
Vega OTTHUMG00000172412
MIM 604114
Ensembl ENSG00000137841
HGNC 9055
HPRD 04985

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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