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Sequence in raw or FASTA format:


Blast Method:


PLOD1 procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000302 Homo sapiens procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (PLOD1), mRNA. GenEZ ORF Cloning On-demand $849.00 20

*Business Day

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Gene Symbol PLOD1
Entrez Gene ID 5351
Full Name procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1
Synonyms FLJ42041, LH, LH1, LLH, PLOD
Gene Type protein-coding
Organism Homo sapiens (human)



Summary Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008].

MIM: 153454

Ehlers-Danlos syndrome, type VI, 225400 (3); Nevo syndrome, 601451

mRNA Protein Product Sequence Price Select
NM_000302, 324710986 NP_000293, 32307144 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor ORF Sequence $700.00
hsa00310Lysine degradation
REACT_118779Extracellular matrix organization
REACT_120729Collagen formation
REACT_121139Collagen biosynthesis and modifying enzymes
Homo sapiens (human)PLOD1NP_000293.2
Pan troglodytes (chimpanzee)PLOD1XP_001142788.1
Canis lupus familiaris (dog)PLOD1XP_544565.2
Bos taurus (cattle)PLOD1NP_776573.1
Mus musculus (house mouse)Plod1NP_035252.1
Rattus norvegicus (Norway rat)Plod1NP_446279.1
Gallus gallus (chicken)PLOD1NP_001005618.1
Danio rerio (zebrafish)plod1aNP_001071210.2
GeneCards PLOD1
UniProt Q02809
MIM 153454
Ensembl ENSG00000083444
HGNC 9081
HPRD 01086

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
lysine hydroxylase
lysyl hydroxlase 1
procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1


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