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CNGB3 cyclic nucleotide gated channel beta 3 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_019098 Homo sapiens cyclic nucleotide gated channel beta 3 (CNGB3), mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Gene Symbol CNGB3
Entrez Gene ID 54714
Full Name cyclic nucleotide gated channel beta 3
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease. [provided by RefSeq, Feb 2010].

MIM: 605080

Achromatopsia-3, 262300 (3); Macular degeneration, juvenile, 248200

mRNA Protein Product Sequence Price Select
NM_019098, 289177194 NP_061971, 116642889 cyclic nucleotide-gated cation channel beta-3 ORF Sequence $750.00
Pathway Interaction Database
cone_pathwayVisual signal transduction: Cones
Homo sapiens (human)CNGB3NP_061971.3
Pan troglodytes (chimpanzee)CNGB3XP_519846.2
Macaca mulatta (Rhesus monkey)CNGB3XP_001083646.1
Canis lupus familiaris (dog)CNGB3NP_001003030.1
Bos taurus (cattle)CNGB3XP_002692873.2
Mus musculus (house mouse)Cngb3NP_038955.1
Rattus norvegicus (Norway rat)Cngb3XP_575779.3
Gallus gallus (chicken)CNGB3XP_425928.3
Danio rerio (zebrafish)LOC562466XP_690937.3
Danio rerio (zebrafish)cngb3XP_691142.3
Drosophila melanogaster (fruit fly)CG17922NP_611607.2
Caenorhabditis eleganstax-2NP_492427.3
GeneCards CNGB3
UniProt Q9NQW8
MIM 605080
Ensembl ENSG00000170289
HGNC 2153
HPRD 05468

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
cyclic nucleotide-gated cation channel beta-3
cyclic nucleotide-gated cation channel beta-3
CNG channel beta-3
cone photoreceptor cGMP-gated cation channel beta-subunit
cyclic nucleotide-gated cation channel modulatory subunit


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