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XAF1 XIAP associated factor 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_017523 Homo sapiens XIAP associated factor 1 (XAF1), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $348.00 $299.00 10
NM_199139 Homo sapiens XIAP associated factor 1 (XAF1), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $449.00 14
XM_005256706 PREDICTED: Homo sapiens XIAP associated factor 1 (XAF1), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $449.00 14
XM_005256707 PREDICTED: Homo sapiens XIAP associated factor 1 (XAF1), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $399.00 14
XM_005256708 PREDICTED: Homo sapiens XIAP associated factor 1 (XAF1), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand $399.00 14
XM_006721550 PREDICTED: Homo sapiens XIAP associated factor 1 (XAF1), transcript variant X5, mRNA. GenEZ ORF Cloning On-demand $399.00 14
XM_006721551 PREDICTED: Homo sapiens XIAP associated factor 1 (XAF1), transcript variant X6, mRNA. GenEZ ORF Cloning On-demand $399.00 14
XM_006721552 PREDICTED: Homo sapiens XIAP associated factor 1 (XAF1), transcript variant X7, mRNA. GenEZ ORF Cloning On-demand $399.00 14

*Business Day

Related Services

Gene Symbol XAF1
Entrez Gene ID 54739
Full Name XIAP associated factor 1
Synonyms BIRC4BP, HSXIAPAF1, XIAPAF1
General protein information
Preferred Names
XIAP-associated factor 1
Names
XIAP-associated factor 1
BIRC4 binding protein
BIRC4-binding protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17p13.1

Summary This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
Disorder

MIM: 606717

mRNA Protein Product Sequence Price Select
NM_017523, 378925606 NP_059993, 40288191 XIAP-associated factor 1 isoform 1 ORF Sequence $199.00
NM_199139, 378925605 NP_954590, 40288193 XIAP-associated factor 1 isoform 2 ORF Sequence $300.00
XM_005256706, 578829966 XP_005256763, 530410452 XIAP-associated factor 1 isoform X2 ORF Sequence $300.00
XM_005256707, 530410453 XP_005256764, 530410454 XIAP-associated factor 1 isoform X3 ORF Sequence $250.00
XM_005256708, 530410455 XP_005256765, 530410456 XIAP-associated factor 1 isoform X4 ORF Sequence $250.00
XM_006721550, 578829967 XP_006721613, 578829968 XIAP-associated factor 1 isoform X5 ORF Sequence $250.00
XM_006721551, 578829969 XP_006721614, 578829970 XIAP-associated factor 1 isoform X6 ORF Sequence $250.00
XM_006721552, 578829971 XP_006721615, 578829972 XIAP-associated factor 1 isoform X7 ORF Sequence $250.00
Reactome
REACT_6900Immune System
REACT_75790Cytokine Signaling in Immune system
REACT_25229Interferon Signaling
REACT_25162Interferon alpha/beta signaling
Homo sapiens (human)XAF1NP_059993.2
Pan troglodytes (chimpanzee)XAF1XP_001168151.2
Macaca mulatta (Rhesus monkey)XAF1XP_001103678.1
Bos taurus (cattle)XAF1NP_001030247.1
Mus musculus (house mouse)Xaf1NP_001032802.2
Rattus norvegicus (Norway rat)XAF1XP_006246917.1
Gallus gallus (chicken)XAF1XP_004946871.1
Danio rerio (zebrafish)zgc:153893NP_001070115.1
Process
IDNameEvidence
GO:0006915apoptotic processIEA
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0031333negative regulation of protein complex assemblyIEA
GO:0035456response to interferon-betaIDA
GO:0060337type I interferon signaling pathwayTAS
Component
IDNameEvidence
GO:0005634nucleusIEA
GO:0005739mitochondrionIEA
GO:0005829cytosolTAS
Function
IDNameEvidence
GO:0008270zinc ion bindingIEA
GeneCards XAF1
UniProt Q6GPH4, B3KPW1
Vega OTTHUMG00000177908
MIM 606717
Ensembl ENSG00000132530
HGNC 30932
HPRD 06978

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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