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PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_177983 Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent, 1G (PPM1G), mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Gene Symbol PPM1G
Entrez Gene ID 5496
Full Name protein phosphatase, Mg2+/Mn2+ dependent, 1G
Synonyms PP2CG, PP2CGAMMA, PPP2CG
General protein information
Preferred Names
protein phosphatase 1G
Names
protein phosphatase 1G
PP2C-gamma
PP2C, gamma
protein phosphatase 1C
protein phosphatase 2C gamma isoform
protein phosphatase 2C isoform gamma
protein phosphatase magnesium-dependent 1 gamma
protein phosphatase 2, catalytic subunit, gamma isoform
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
NP_817092.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p23.3

Summary The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010].
Disorder

MIM: 605119

mRNA Protein Product Sequence Price Select
NM_177983, 386869321 NP_817092, 29826282 protein phosphatase 1G ORF Sequence $550.00
WikiPathways
WP411mRNA processing
Homo sapiens (human)PPM1GNP_817092.1
Pan troglodytes (chimpanzee)PPM1GNP_001233384.1
Macaca mulatta (Rhesus monkey)PPM1GXP_001096179.1
Canis lupus familiaris (dog)PPM1GXP_532910.2
Bos taurus (cattle)PPM1GNP_777226.2
Mus musculus (house mouse)Ppm1gNP_032040.1
Rattus norvegicus (Norway rat)Ppm1gNP_671742.1
Gallus gallus (chicken)PPM1GXP_003641098.1
Danio rerio (zebrafish)ppm1gNP_958896.1
Drosophila melanogaster (fruit fly)CG10417NP_610169.1
Xenopus (Silurana) tropicalis (western clawed frog)ppm1gNP_001015840.1
Process
IDNameEvidence
GO:0006470protein dephosphorylationTAS
GO:0007050cell cycle arrestIEA
GO:0035970peptidyl-threonine dephosphorylationIDA
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIEA
Function
IDNameEvidence
GO:0004722protein serine/threonine phosphatase activityIDA
GO:0005515protein bindingIPI
GO:0046872metal ion bindingIEA
GeneCards PPM1G
UniProt Q6IAU5, O15355
Vega OTTHUMG00000097788
MIM 605119
Ensembl ENSG00000115241
HGNC 9278
HPRD 09237

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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