Aatf apoptosis antagonizing transcription factor [Mus musculus (house mouse)]
| Gene Symbol | Aatf |
| Entrez Gene ID | 56321 |
| Full Name | apoptosis antagonizing transcription factor |
| Synonyms | 4933415H02Rik, 5830465M17Rik, Che-1, MGC35916, Trb |
| Gene Type | protein-coding |
| Organism | Mus musculus (house mouse) |
| Genome |
11 11|11 B5 |
| Summary | |
| Disorder | MIM: |
| 1210653 | p75 NTR receptor-mediated signalling |
| 1210660 | Cell death signalling via NRAGE, NRIF and NADE |
| 1210190 | Signalling by NGF |
| 1210661 | NRAGE signals death through JNK |
| Homo sapiens (human) | AATF | NP_036270.1 |
| Pan troglodytes (chimpanzee) | AATF | XP_511427.2 |
| Canis lupus familiaris (dog) | AATF | XP_537715.2 |
| Bos taurus (cattle) | AATF | XP_001252958.2 |
| Mus musculus (house mouse) | Aatf | NP_062790.1 |
| Rattus norvegicus (Norway rat) | Aatf | NP_446172.1 |
| Gallus gallus (chicken) | AATF | NP_001025895.1 |
| Danio rerio (zebrafish) | aatf | NP_001077297.2 |
| Drosophila melanogaster (fruit fly) | CG11188 | NP_609066.1 |
| Caenorhabditis elegans | Y73E7A.2 | NP_490870.2 |
| Arabidopsis thaliana (thale cress) | AT5G61330 | NP_200941.2 |
| ID | Name | Evidence |
| GO:0006351 | transcription, DNA-dependent | ISO |
| GO:0006915 | apoptosis | ISO |
| GO:0006916 | anti-apoptosis | ISO |
| GO:0007155 | cell adhesion | IMP |
| GO:0007346 | regulation of mitotic cell cycle | IMP |
| GO:0008624 | induction of apoptosis by extracellular signals | ISO |
| GO:0032929 | negative regulation of superoxide anion generation | ISO |
| GO:0040016 | embryonic cleavage | IMP |
| GO:0042254 | ribosome biogenesis | IMP |
| GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process | IDA |
| GO:0045893 | positive regulation of transcription, DNA-dependent | ISO |
| GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | ISO |
| GO:2000378 | negative regulation of reactive oxygen species metabolic process | ISO |
Component
| ID | Name | Evidence |
| GO:0005634 | nucleus | IDA |
| GO:0005634 | nucleus | ISO |
| GO:0005730 | nucleolus | IDA |
| GO:0005730 | nucleolus | ISO |
| GO:0005737 | cytoplasm | IDA |
| GO:0005737 | cytoplasm | ISO |
| GO:0005794 | Golgi apparatus | ISO |
| GO:0005813 | centrosome | ISO |
| GO:0005829 | cytosol | EXP |
| GO:0005925 | focal adhesion | ISO |
Function
| ID | Name | Evidence |
| GO:0003700 | sequence-specific DNA binding transcription factor activity | ISO |
| GO:0005515 | protein binding | IPI |
| GO:0019904 | protein domain specific binding | ISO |
| GO:0043522 | leucine zipper domain binding | ISO |
| GO:0048156 | tau protein binding | ISO |
| GeneCards | Aatf |
| UniProt | Q9JKX4 |
| MGI | 1929608 |
| Ensembl | ENSMUSG00000018697 |
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