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Gsk3b glycogen synthase kinase 3 beta [Mus musculus (house mouse)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_019827 Mus musculus glycogen synthase kinase 3 beta (Gsk3b), mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
XM_006522425 PREDICTED: Mus musculus glycogen synthase kinase 3 beta (Gsk3b), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006522426 PREDICTED: Mus musculus glycogen synthase kinase 3 beta (Gsk3b), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $549.00 14

*Business Day

Related Services

Gene Symbol Gsk3b
Entrez Gene ID 56637
Full Name glycogen synthase kinase 3 beta
Synonyms 7330414F15Rik, 8430431H08Rik, C86142, GSK-3, GSK-3beta, GSK3
General protein information
Preferred Names
glycogen synthase kinase-3 beta
Names
glycogen synthase kinase-3 beta
GSK-3 beta
serine/threonine-protein kinase GSK3B
NP_062801.1
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

16

16|16 B4

Summary
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_019827, 158508595 NP_062801, 9790077 glycogen synthase kinase-3 beta ORF Sequence $360.00
XM_006522425, 568995941 XP_006522488, 568995942 glycogen synthase kinase-3 beta isoform X1 ORF Sequence $550.00
XM_006522426, 568995943 XP_006522489, 568995944 glycogen synthase kinase-3 beta isoform X2 ORF Sequence $400.00
KEGG
mmu04310Wnt signaling pathway
mmu04012ErbB signaling pathway
mmu04110Cell cycle
mmu04360Axon guidance
mmu04662B cell receptor signaling pathway
mmu04340Hedgehog signaling pathway
mmu04660T cell receptor signaling pathway
mmu04510Focal adhesion
mmu05010Alzheimer's disease
mmu05213Endometrial cancer
mmu04910Insulin signaling pathway
mmu04916Melanogenesis
mmu05200Pathways in cancer
mmu05210Colorectal cancer
mmu05215Prostate cancer
mmu05217Basal cell carcinoma
mmu04062Chemokine signaling pathway
mmu04722Neurotrophin signaling pathway
mmu05160Hepatitis C
mmu05166HTLV-I infection
mmu05162Measles
mmu05164Influenza A
mmu04728Dopaminergic synapse
mmu04151PI3K-Akt signaling pathway
mmu04390Hippo signaling pathway
mmu05169Epstein-Barr virus infection
mmu04917Prolactin signaling pathway
mmu04932Non-alcoholic fatty liver disease (NAFLD)
mmu04919Thyroid hormone signaling pathway
WikiPathways
WP151IL-5 Signaling Pathway
WP387IL-6 signaling Pathway
WP317Glycogen Metabolism
WP274B Cell Receptor Signaling Pathway
WP403Wnt Signaling Pathway
WP265Delta-Notch Signaling Pathway
WP1763PluriNetWork
WP297IL-7 Signaling Pathway
WP1560MicroRNAs in cardiomyocyte hypertrophy
WP85Focal Adhesion
WP339ESC Pluripotency Pathways
WP1267Senescence and Autophagy
WP539Wnt Signaling Pathway NetPath
WP65Insulin Signaling
WP1261ErbB signaling pathway
WP723Wnt Signaling Pathway and Pluripotency
WP246TNF-alpha NF-kB Signaling Pathway
WP190Cell cycle
WP373IL-3 Signaling Pathway
WP2292Chemokine signaling pathway
WP2309XPodNet - protein-protein interactions in the podocyte expanded by STRING
LIPID MAPS
PI3KPI3K/Akt/mTOR signaling pathway
CellCycleCell cycle signaling pathway
Reactome
5605939Constitutive PI3K/AKT Signaling in Cancer
5604931Signaling by ERBB4
5605985Regulation of HSF1-mediated heat shock response
5605986Cellular response to heat stress
5605585CRMPs in Sema3A signaling
5604598Cell Cycle, Mitotic
5604599Cell Cycle
5605377AKT phosphorylates targets in the cytosol
5605503Semaphorin interactions
5605369PI3K events in ERBB4 signaling
5605363PI3K/AKT activation
5604608S Phase
5604793Signaling by FGFR
5604790Signaling by PDGF
5604789Downstream signal transduction
5604788Signalling by NGF
5604792Downstream signaling of activated FGFR
5604807Signaling by the B Cell Receptor (BCR)
5605368Downstream signaling events of B Cell Receptor (BCR)
5604802Innate Immune System
5604647Disease
5605367PIP3 activates AKT signaling
5604803Immune System
5605352Degradation of beta-catenin by the destruction complex
5605190Signaling by Wnt
5604808Adaptive Immune System
5604774Signal Transduction
5604797Signaling by EGFR in Cancer
5605372Role of LAT2/NTAL/LAB on calcium mobilization
5604794Signaling by FGFR in disease
5604796Signaling by EGFR
5604924Developmental Biology
5604800DAP12 signaling
5604801DAP12 interactions
5604932Signaling by SCF-KIT
5605353Beta-catenin phosphorylation cascade
5604923Axon guidance
5604810Fc epsilon receptor (FCERI) signaling
5604787NGF signalling via TRKA from the plasma membrane
5605273PI-3K cascade
5604799Signaling by ERBB2
5605272GAB1 signalosome
5604856Ubiquitin-dependent degradation of Cyclin D
5604855Ubiquitin-dependent degradation of Cyclin D1
5605399disassembly of the destruction complex and recruitment of AXIN to the membrane
5605398TCF dependent signaling in response to WNT
5605371PI3K/AKT Signaling in Cancer
5605370PI3K events in ERBB2 signaling
5604632Cellular responses to stress
Homo sapiens (human)GSK3BNP_002084.2
Pan troglodytes (chimpanzee)GSK3BXP_003339094.1
Canis lupus familiaris (dog)GSK3BXP_535751.2
Bos taurus (cattle)GSK3BNP_001094780.1
Mus musculus (house mouse)Gsk3bNP_062801.1
Rattus norvegicus (Norway rat)Gsk3bNP_114469.1
Gallus gallus (chicken)GSK3BXP_416557.4
Danio rerio (zebrafish)gsk3bNP_571456.1
Caenorhabditis elegansgsk-3NP_493243.1
Arabidopsis thaliana (thale cress)SK13NP_196968.2
Xenopus (Silurana) tropicalis (western clawed frog)gsk3bXP_002941025.2
Process
IDNameEvidence
GO:0000320re-entry into mitotic cell cycleIDA
GO:0001837epithelial to mesenchymal transitionISO
GO:0001954positive regulation of cell-matrix adhesionISO
GO:0005975carbohydrate metabolic processIEA
GO:0005977glycogen metabolic processISO
GO:0006349regulation of gene expression by genetic imprintingIMP
GO:0006468protein phosphorylationIDA
GO:0006468protein phosphorylationIGI
GO:0006468protein phosphorylationIMP
GO:0006468protein phosphorylationISO
GO:0006468protein phosphorylationISS
GO:0006611protein export from nucleusIDA
GO:0006983ER overload responseIDA
GO:0006983ER overload responseISO
GO:0007010cytoskeleton organizationTAS
GO:0007163establishment or maintenance of cell polarityISO
GO:0007275multicellular organismal developmentIEA
GO:0007399nervous system developmentIEA
GO:0007409axonogenesisIGI
GO:0007520myoblast fusionIDA
GO:0007520myoblast fusionIGI
GO:0007623circadian rhythmIMP
GO:0008283cell proliferationTAS
GO:0009887organ morphogenesisIMP
GO:0009968negative regulation of signal transductionIEA
GO:0010614negative regulation of cardiac muscle hypertrophyIDA
GO:0010800positive regulation of peptidyl-threonine phosphorylationIDA
GO:0010977negative regulation of neuron projection developmentIGI
GO:0010977negative regulation of neuron projection developmentIMP
GO:0014043negative regulation of neuron maturationIGI
GO:0014902myotube differentiationIGI
GO:0016055Wnt signaling pathwayIGI
GO:0016310phosphorylationIMP
GO:0016477cell migrationIGI
GO:0018105peptidyl-serine phosphorylationIDA
GO:0018105peptidyl-serine phosphorylationISO
GO:0021766hippocampus developmentISO
GO:0030010establishment of cell polarityISO
GO:0030154cell differentiationIEA
GO:0031333negative regulation of protein complex assemblyISO
GO:0031334positive regulation of protein complex assemblyISO
GO:0032091negative regulation of protein bindingISO
GO:0032092positive regulation of protein bindingIDA
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic processIGI
GO:0032855positive regulation of Rac GTPase activityISO
GO:0032886regulation of microtubule-based processIDA
GO:0032886regulation of microtubule-based processISO
GO:0033138positive regulation of peptidyl-serine phosphorylationIDA
GO:0035372protein localization to microtubuleIGI
GO:0035556intracellular signal transductionISO
GO:0036016cellular response to interleukin-3IDA
GO:0043065positive regulation of apoptotic processISO
GO:0043066negative regulation of apoptotic processIMP
GO:0043066negative regulation of apoptotic processISO
GO:0043407negative regulation of MAP kinase activityISO
GO:0044027hypermethylation of CpG islandIMP
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic processIMP
GO:0045444fat cell differentiationIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIMP
GO:0046827positive regulation of protein export from nucleusISO
GO:0048168regulation of neuronal synaptic plasticityISO
GO:0048511rhythmic processIEA
GO:0050774negative regulation of dendrite morphogenesisISO
GO:0051534negative regulation of NFAT protein import into nucleusISO
GO:0060070canonical Wnt signaling pathwayIDA
GO:0060070canonical Wnt signaling pathwayISO
GO:0071109superior temporal gyrus developmentISO
GO:0071260cellular response to mechanical stimulusISO
GO:0097192extrinsic apoptotic signaling pathway in absence of ligandIDA
GO:1901030positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayIDA
GO:2000738positive regulation of stem cell differentiationIMP
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005737cytoplasmISO
GO:0005813centrosomeISO
GO:0005829cytosolIDA
GO:0005829cytosolISO
GO:0005886plasma membraneISO
GO:0016020membraneISO
GO:0030426growth coneIDA
GO:0030529ribonucleoprotein complexIDA
GO:0030877beta-catenin destruction complexIDA
GO:0030877beta-catenin destruction complexISO
GO:0043025neuronal cell bodyIDA
GO:0043197dendritic spineISO
GO:0043198dendritic shaftIDA
GO:0043227membrane-bounded organelleIDA
GO:0043234protein complexISO
GO:0044297cell bodyIDA
GO:0045121membrane raftISO
GO:0048471perinuclear region of cytoplasmIDA
Function
IDNameEvidence
GO:0000166nucleotide bindingIEA
GO:0001085RNA polymerase II transcription factor bindingISO
GO:0002039p53 bindingISO
GO:0004672protein kinase activityIDA
GO:0004674protein serine/threonine kinase activityIDA
GO:0004674protein serine/threonine kinase activityIMP
GO:0004674protein serine/threonine kinase activityISO
GO:0004674protein serine/threonine kinase activityISS
GO:0005178integrin bindingISO
GO:0005515protein bindingIPI
GO:0005524ATP bindingISO
GO:0008013beta-catenin bindingIPI
GO:0008013beta-catenin bindingISO
GO:0016301kinase activityISO
GO:0016740transferase activityIEA
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA
GO:0019901protein kinase bindingISO
GO:0031625ubiquitin protein ligase bindingISO
GO:0034236protein kinase A catalytic subunit bindingISO
GO:0035255ionotropic glutamate receptor bindingISO
GO:0048156tau protein bindingISO
GO:0050321tau-protein kinase activityIDA
GO:0050321tau-protein kinase activityISO
GO:0051059NF-kappaB bindingISO
GeneCards Gsk3b
PDB 4NU1
UniProt Q5KU03, E9QAQ5, Q9WV60
MGI 1861437
Vega OTTMUSG00000016276
Ensembl ENSMUSG00000022812

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

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