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Sequence in raw or FASTA format:


Blast Method:


PTH parathyroid hormone [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu27358D NM_000315 Homo sapiens parathyroid hormone (PTH), mRNA. pcDNA3.1-C-(k)DYK In-stock 5-7 Starting from $99
OHu27358C NM_000315 Homo sapiens parathyroid hormone (PTH), mRNA. Customized vector In-stock 5-7 Starting from $99

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Gene Symbol PTH
Entrez Gene ID 5741
Full Name parathyroid hormone
Synonyms PTH1
General protein information
Preferred Names
parathyroid hormone
parathyroid hormone
parathyroid hormone 1
preproparathyroid hormone
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH). [provided by RefSeq, Jul 2008].

MIM: 168450

Hypoparathyroidism, autosomal dominant, 146200 (3);

mRNA Protein Product Sequence Price Select
NM_000315, 39995098 NP_000306, 4506267 parathyroid hormone preproprotein ORF Sequence $99.00
WP1531Vitamin D synthesis
WP474Endochondral Ossification
WP322Osteoblast Signaling
REACT_19184GPCR downstream signaling
REACT_19327G alpha (s) signalling events
REACT_14797Signaling by GPCR
REACT_18372Class B/2 (Secretin family receptors)
REACT_21340GPCR ligand binding
REACT_111102Signal Transduction
Homo sapiens (human)PTHNP_000306.1
Pan troglodytes (chimpanzee)PTHXP_003951890.1
Macaca mulatta (Rhesus monkey)PTHXP_001094024.1
Canis lupus familiaris (dog)PTHNP_001003302.1
Bos taurus (cattle)PTHNP_776379.2
Mus musculus (house mouse)PthNP_065648.1
Rattus norvegicus (Norway rat)PthNP_058740.1
Gallus gallus (chicken)PTHNP_990783.1
GO:0000122negative regulation of transcription from RNA polymerase II promoterIDA
GO:0001501skeletal system developmentTAS
GO:0006366transcription from RNA polymerase II promoterIMP
GO:0006874cellular calcium ion homeostasisIEA
GO:0007186G-protein coupled receptor signaling pathwayTAS
GO:0007189adenylate cyclase-activating G-protein coupled receptor signaling pathwayIEA
GO:0007266Rho protein signal transductionIEA
GO:0007267cell-cell signalingIEA
GO:0008628hormone-mediated apoptotic signaling pathwayTAS
GO:0009967positive regulation of signal transductionIEA
GO:0010288response to lead ionIEA
GO:0010468regulation of gene expressionIDA
GO:0030501positive regulation of bone mineralizationIDA
GO:0030819positive regulation of cAMP biosynthetic processIDA
GO:0033280response to vitamin DIEA
GO:0034645cellular macromolecule biosynthetic processIDA
GO:0042493response to drugIEA
GO:0045453bone resorptionNAS
GO:0045471response to ethanolIEA
GO:0045725positive regulation of glycogen biosynthetic processIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0046058cAMP metabolic processTAS
GO:0046326positive regulation of glucose importIDA
GO:0046686response to cadmium ionIEA
GO:0071107response to parathyroid hormoneIEA
GO:0071774response to fibroblast growth factorIEA
GO:0005576extracellular regionNAS
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIEA
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIMP
GO:0005179hormone activityIEA
GO:0031857type 1 parathyroid hormone receptor bindingIEA
GO:0051428peptide hormone receptor bindingIDA
GeneCards PTH
PDB 1ZWF, 1HPY, 1ZWG, 1ET2, 2L1X, 1HTH, 1BWX, 1ZWA, 1ZWE, 1ZWB, 1FVY, 1ZWD, 3C4M, 1ET1, 1HPH
UniProt P01270
Vega OTTHUMG00000165785
MIM 168450
Ensembl ENSG00000152266
HGNC 9606
HPRD 01345

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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