XPO5 exportin 5 [Homo sapiens (human)]
| Gene Symbol | XPO5 |
| Entrez Gene ID | 57510 |
| Full Name | exportin 5 |
| Synonyms | FLJ14239, FLJ32057, FLJ45606, KIAA1291 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
6 6p21.1 |
| Summary | Exportin-5 belongs to a large family of karyopherins (see MIM 602738) that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments.[supplied by OMIM]. |
| Disorder | MIM: 607845 |
| hsa03013 | RNA transport |
Reactome
| REACT_12472 | Regulatory RNA pathways |
| REACT_12417 | MicroRNA (miRNA) Biogenesis |
| Homo sapiens (human) | XPO5 | NP_065801.1 |
| Canis lupus familiaris (dog) | XPO5 | XP_532148.2 |
| Bos taurus (cattle) | XPO5 | XP_001790589.1 |
| Mus musculus (house mouse) | Xpo5 | NP_082474.1 |
| Gallus gallus (chicken) | XPO5 | XP_419501.2 |
| Danio rerio (zebrafish) | xpo5 | XP_001921422.2 |
| Drosophila melanogaster (fruit fly) | Ranbp21 | NP_608339.2 |
| Arabidopsis thaliana (thale cress) | HST | NP_187155.2 |
| ID | Name | Evidence |
| GO:0006611 | protein export from nucleus | IEA |
| GO:0006886 | intracellular protein transport | IEA |
| GO:0031047 | gene silencing by RNA | IEA |
Component
| ID | Name | Evidence |
| GO:0005634 | nucleus | IDA |
| GO:0005654 | nucleoplasm | TAS |
| GO:0005730 | nucleolus | IDA |
| GO:0005737 | cytoplasm | IDA |
| GO:0005829 | cytosol | TAS |
Function
| ID | Name | Evidence |
| GO:0000049 | tRNA binding | IEA |
| GO:0003723 | RNA binding | TAS |
| GO:0005515 | protein binding | IPI |
| GO:0008565 | protein transporter activity | IEA |
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