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SPTBN4 spectrin, beta, non-erythrocytic 4 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_020971 Homo sapiens spectrin, beta, non-erythrocytic 4 (SPTBN4), transcript variant sigma1, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_025213 Homo sapiens spectrin, beta, non-erythrocytic 4 (SPTBN4), transcript variant sigma5, mRNA. GenEZ ORF Cloning On-demand $849.00 20

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Related Services

Gene Symbol SPTBN4
Entrez Gene ID 57731
Full Name spectrin, beta, non-erythrocytic 4
Synonyms KIAA1642, QV, SPNB4, SPTBN3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.13

Summary Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 606214

mRNA Protein Product Sequence Price Select
NM_020971, 115430236 NP_066022, 115430237 spectrin beta chain, non-erythrocytic 4 isoform sigma1 ORF Sequence $3500.00
NM_025213, 115430238 NP_079489, 115430239 spectrin beta chain, non-erythrocytic 4 isoform sigma5 ORF Sequence $700.00
Reactome
REACT_22205L1CAM interactions
REACT_22266Interaction between L1 and Ankyrins
REACT_111045Developmental Biology
REACT_18266Axon guidance
REACT_18334NCAM signaling for neurite out-growth
Homo sapiens (human)SPTBN4NP_066022.2
Macaca mulatta (Rhesus monkey)SPTBN4XP_002801295.1
Canis lupus familiaris (dog)SPTBN4XP_541613.2
Bos taurus (cattle)SPTBN4NP_001179839.1
Mus musculus (house mouse)Spnb4NP_115999.2
Rattus norvegicus (Norway rat)Sptbn4XP_218364.5
GeneCards SPTBN4
UniProt Q9H254
MIM 606214
Ensembl ENSG00000160460
HGNC 14896
HPRD 09372

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
spectrin beta chain, non-erythrocytic 4
Names
spectrin beta chain, non-erythrocytic 4
beta-IV spectrin
spectrin beta chain, brain 3
spectrin, non-erythroid beta chain 3

Interactant



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