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OPN1LW opsin 1 (cone pigments), long-wave-sensitive [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu21082 NM_020061 Homo sapiens opsin 1 (cone pigments), long-wave-sensitive (OPN1LW), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu21082C NM_020061 Homo sapiens opsin 1 (cone pigments), long-wave-sensitive (OPN1LW), mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol OPN1LW
Entrez Gene ID 5956
Full Name opsin 1 (cone pigments), long-wave-sensitive
Synonyms CBBM, CBP, COD5, RCP, ROP
General protein information
Preferred Names
long-wave-sensitive opsin 1
Names
long-wave-sensitive opsin 1
red-sensitive opsin
cone dystrophy 5 (X-linked)
red cone photoreceptor pigment
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq28

Summary This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called red cone photopigment or long-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. This gene and the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of partial, protanopic colorblindness. [provided by RefSeq, Jul 2008].
Disorder

MIM: 300822

Colorblindness, protan, 303900 (3); Blue cone monochromacy, 303700

mRNA Protein Product Sequence Price Select
NM_020061, 539848520 NP_064445, 539848521 long-wave-sensitive opsin 1 ORF Sequence $400.00
WikiPathways
WP455GPCRs, Class A Rhodopsin-like
Reactome
REACT_19184GPCR downstream signaling
REACT_19231G alpha (i) signalling events
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_14797Signaling by GPCR
REACT_18426Opsins
REACT_21340GPCR ligand binding
REACT_111102Signal Transduction
REACT_116125Disease
REACT_160102Diseases associated with visual transduction
REACT_160083The retinoid cycle in cones (daylight vision)
REACT_160125Visual phototransduction
REACT_160130Retinoid cycle disease events
Homo sapiens (human)OPN1LWNP_064445.2
Pan troglodytes (chimpanzee)OPN1LWXP_003317827.1
Canis lupus familiaris (dog)OPN1LWNP_001184001.1
Bos taurus (cattle)OPN1LWNP_776991.1
Mus musculus (house mouse)Opn1mwNP_032132.1
Rattus norvegicus (Norway rat)Opn1mwNP_446000.1
Gallus gallus (chicken)OPN1LWNP_990771.1
Danio rerio (zebrafish)opn1lw2NP_001002443.1
Danio rerio (zebrafish)opn1lw1NP_571250.1
Xenopus (Silurana) tropicalis (western clawed frog)opn1lwNP_001096331.1
Process
IDNameEvidence
GO:0001523retinoid metabolic processTAS
GO:0007165signal transductionTAS
GO:0007186G-protein coupled receptor signaling pathwayIEA
GO:0007601visual perceptionIEA
GO:0007603phototransduction, visible lightTAS
GO:0018298protein-chromophore linkageIEA
GO:0032467positive regulation of cytokinesisIMP
Component
IDNameEvidence
GO:0005887integral component of plasma membraneTAS
GO:0042622photoreceptor outer segment membraneTAS
Function
IDNameEvidence
GO:0004930G-protein coupled receptor activityIEA
GO:0009881photoreceptor activityIEA
GeneCards OPN1LW
Vega OTTHUMG00000034295
MIM 300822
Ensembl ENSG00000102076
HGNC 9936
HPRD 02366

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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