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Sequence in raw or FASTA format:


Blast Method:


RMRP RNA component of mitochondrial RNA processing endoribonuclease [Homo sapiens (human)]

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Gene Symbol RMRP
Entrez Gene ID 6023
Full Name RNA component of mitochondrial RNA processing endoribonuclease
Synonyms CHH, NME1, RMRPR, RRP2
General protein information
Gene Type ncRNA
Organism Homo sapiens (human)




MIM: 157660

Cartilage-hair hypoplasia, 250250 (3); Metaphyseal dysplasia without

mRNA Protein Product Sequence Price Select
GeneCards RMRP
MIM 157660
Ensembl ENSG00000269900
HGNC 10031

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the RMRP gene?

Unlike many genes, the RMRP gene does not contain instructions for making a protein. Instead, a molecule called a noncoding RNA, a chemical cousin of DNA, is produced from the RMRP gene. This RNA attaches (binds) to several proteins, forming an enzyme called mitochondrial RNA-processing endoribonuclease, or RNase MRP.

The RNase MRP enzyme is thought to be involved in several important processes in the cell. For example, it likely helps copy (replicate) the DNA found in the energy-producing centers of cells (mitochondria). The RNase MRP enzyme probably also processes ribosomal RNA, which is required for assembling protein building blocks (amino acids) into functioning proteins. In addition, this enzyme helps control the cell cycle, which is the cell's way of replicating itself in an organized, step-by-step fashion.


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