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HPSE2 heparanase 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001166244 Homo sapiens heparanase 2 (HPSE2), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001166245 Homo sapiens heparanase 2 (HPSE2), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001166246 Homo sapiens heparanase 2 (HPSE2), transcript variant 4, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_021828 Homo sapiens heparanase 2 (HPSE2), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $849.00 20

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Gene Symbol HPSE2
Entrez Gene ID 60495
Full Name heparanase 2
Synonyms FLJ11684, FLJ44022, HPA2, HPR2, MGC133234, UFS
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

10

10q23-q24

Summary This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
Disorder

MIM: 613469

Urofacial syndrome, 236730 (3)

mRNA Protein Product Sequence Price Select
NM_001166244, 261878502 NP_001159716, 261878503 inactive heparanase-2 isoform 2 ORF Sequence $550.00
NM_001166245, 261878504 NP_001159717, 261878505 inactive heparanase-2 isoform 3 ORF Sequence $550.00
NM_001166246, 261878506 NP_001159718, 261878507 inactive heparanase-2 isoform 4 ORF Sequence $550.00
NM_021828, 261878500 NP_068600, 261878501 inactive heparanase-2 isoform 1 ORF Sequence $700.00
KEGG
hsa00531Glycosaminoglycan degradation
hsa_M00078Heparan sulfate degradation
M00078Heparan sulfate degradation
Reactome
REACT_147798MPS IV - Morquio syndrome B
REACT_147788MPS IIIB - Sanfilippo syndrome B
REACT_147857MPS I - Hurler syndrome
REACT_147719MPS VI - Maroteaux-Lamy syndrome
REACT_147734MPS II - Hunter syndrome
REACT_147739MPS IX - Natowicz syndrome
REACT_147749MPS IIID - Sanfilippo syndrome D
REACT_147753MPS IIIA - Sanfilippo syndrome A
REACT_147759MPS VII - Sly syndrome
REACT_116125Disease
REACT_121314Heparan sulfate/heparin (HS-GAG) metabolism
REACT_147853Mucopolysaccharidoses
REACT_120752HS-GAG degradation
REACT_474Metabolism of carbohydrates
REACT_111217Metabolism
REACT_121315Glycosaminoglycan metabolism
REACT_147860MPS IIIC - Sanfilippo syndrome C
REACT_147825MPS IV - Morquio syndrome A
Homo sapiens (human)HPSE2NP_068600.4
Pan troglodytes (chimpanzee)HPSE2XP_001166372.1
Canis lupus familiaris (dog)HPSE2XP_850311.1
Bos taurus (cattle)HPSE2XP_003587919.1
Mus musculus (house mouse)Hpse2NP_001074726.1
Rattus norvegicus (Norway rat)Hpse2NP_001129234.1
Gallus gallus (chicken)HPSE2XP_421704.2
Danio rerio (zebrafish)hpse2XP_691045.2
GeneCards HPSE2
UniProt Q8WWQ2, Q2M1H9
MIM 613469
Ensembl ENSG00000172987
HGNC 18374
HPRD 13669

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Interactant



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