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SCN9A sodium channel, voltage-gated, type IX, alpha subunit [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu22884 NM_002977 Homo sapiens sodium channel, voltage-gated, type IX, alpha subunit (SCN9A), mRNA. pcDNA3.1+-DYK On-demand 30 $2699.00
OHu36521 XM_005246757 PREDICTED: Homo sapiens sodium channel, voltage-gated, type IX, alpha subunit (SCN9A), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 30 $2699.00
OHu22884C NM_002977 Homo sapiens sodium channel, voltage-gated, type IX, alpha subunit (SCN9A), mRNA. Customized vector On-demand 30 $2699.00
OHu36521C XM_005246757 PREDICTED: Homo sapiens sodium channel, voltage-gated, type IX, alpha subunit (SCN9A), transcript variant X1, mRNA. Customized vector On-demand 30 $2699.00

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Gene Symbol SCN9A
Entrez Gene ID 6335
Full Name sodium channel, voltage-gated, type IX, alpha subunit
Synonyms ETHA, FEB3B, GEFSP7, NE-NA, NENA, Nav1.7, PN1, SFNP
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q24

Summary This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009].
Disorder

MIM: 603415

Erythermalgia, primary, 133020 (3); Insensitivity to pain,

mRNA Protein Product Sequence Price Select
NM_002977, 256017191 NP_002968, 4506813 sodium channel protein type 9 subunit alpha ORF Sequence $2500.00
XM_005246757, 530370759 XP_005246814, 530370760 sodium channel protein type 9 subunit alpha isoform X1 ORF Sequence $2500.00
Reactome
REACT_18266Axon guidance
REACT_22205L1CAM interactions
REACT_22266Interaction between L1 and Ankyrins
REACT_111045Developmental Biology
Homo sapiens (human)SCN9ANP_002968.1
Pan troglodytes (chimpanzee)SCN9AXP_003309333.2
Macaca mulatta (Rhesus monkey)SCN9AXP_001101662.2
Canis lupus familiaris (dog)SCN9AXP_005640317.1
Bos taurus (cattle)SCN9ANP_001104257.1
Mus musculus (house mouse)Scn9aNP_061340.2
Rattus norvegicus (Norway rat)Scn9aNP_579823.1
Gallus gallus (chicken)SCN9AXP_004942840.1
Xenopus (Silurana) tropicalis (western clawed frog)scn2aXP_002939316.2
Process
IDNameEvidence
GO:0006814sodium ion transportTAS
GO:0006954inflammatory responseIEA
GO:0009636response to toxic substanceIEA
GO:0009791post-embryonic developmentIEA
GO:0019228neuronal action potentialIBA
GO:0034765regulation of ion transmembrane transportIEA
GO:0035725sodium ion transmembrane transportIBA
GO:0048266behavioral response to painIEA
GO:0086010membrane depolarization during action potentialIBA
Component
IDNameEvidence
GO:0001518voltage-gated sodium channel complexIEA
GO:0005886plasma membraneIBA
Function
IDNameEvidence
GO:0005248voltage-gated sodium channel activityIBA
GO:0031402sodium ion bindingIEA
GeneCards SCN9A
UniProt Q15858
Vega OTTHUMG00000154044
MIM 603415
Ensembl ENSG00000169432
HGNC 10597
HPRD 04565

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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