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Blast Method:


SIX1 SIX homeobox 1 [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu26939D NM_005982 Homo sapiens SIX homeobox 1 (SIX1), mRNA. pcDNA3.1-C-(k)DYK On-demand 7-9 Starting from $99
OHu26939C NM_005982 Homo sapiens SIX homeobox 1 (SIX1), mRNA. Customized vector On-demand 7-9 Starting from $99

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Gene Symbol SIX1
Entrez Gene ID 6495
Full Name SIX homeobox 1
Synonyms BOS3, DFNA23, TIP39
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3). [provided by RefSeq, Jul 2008].

MIM: 601205

Brachiootic syndrome 3, 608389 (3); Deafness, autosomal dominant 23,

mRNA Protein Product Sequence Price Select
NM_005982, 186928837 NP_005973, 5174681 homeobox protein SIX1 ORF Sequence $300.00
hsa05202Transcriptional misregulation in cancer
Homo sapiens (human)SIX1NP_005973.1
Pan troglodytes (chimpanzee)SIX1XP_509988.2
Macaca mulatta (Rhesus monkey)SIX1XP_001096585.1
Canis lupus familiaris (dog)SIX1XP_547841.3
Bos taurus (cattle)SIX1XP_002691065.3
Mus musculus (house mouse)Six1NP_033215.2
Rattus norvegicus (Norway rat)Six1NP_446211.1
Gallus gallus (chicken)SIX1NP_001038150.1
Danio rerio (zebrafish)six1bNP_996978.1
Drosophila melanogaster (fruit fly)soNP_476733.1
Xenopus (Silurana) tropicalis (western clawed frog)six1NP_001093693.1
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA
GO:0001657ureteric bud developmentISS
GO:0001658branching involved in ureteric bud morphogenesisISS
GO:0001759organ inductionISS
GO:0001822kidney developmentISS
GO:0003151outflow tract morphogenesisIEA
GO:0006351transcription, DNA-templatedIEA
GO:0006355regulation of transcription, DNA-templatedISS
GO:0006915apoptotic processIEA
GO:0007389pattern specification processISS
GO:0007519skeletal muscle tissue developmentISS
GO:0007605sensory perception of soundIEA
GO:0008582regulation of synaptic growth at neuromuscular junctionIEA
GO:0021610facial nerve morphogenesisIEA
GO:0030855epithelial cell differentiationISS
GO:0030878thyroid gland developmentISS
GO:0032880regulation of protein localizationIEA
GO:0034504protein localization to nucleusIDA
GO:0035909aorta morphogenesisIEA
GO:0042472inner ear morphogenesisISS
GO:0042474middle ear morphogenesisIEA
GO:0043524negative regulation of neuron apoptotic processISS
GO:0045664regulation of neuron differentiationISS
GO:0045893positive regulation of transcription, DNA-templatedISS
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0048538thymus developmentISS
GO:0048665neuron fate specificationIEA
GO:0048699generation of neuronsISS
GO:0048701embryonic cranial skeleton morphogenesisISS
GO:0048704embryonic skeletal system morphogenesisISS
GO:0048839inner ear developmentISS
GO:0051451myoblast migrationISS
GO:0060037pharyngeal system developmentIEA
GO:0071599otic vesicle developmentIEA
GO:0072075metanephric mesenchyme developmentISS
GO:0072095regulation of branch elongation involved in ureteric bud branchingISS
GO:0072107positive regulation of ureteric bud formationISS
GO:0072172mesonephric tubule formationISS
GO:0072193ureter smooth muscle cell differentiationIEA
GO:0072513positive regulation of secondary heart field cardioblast proliferationIEA
GO:0090103cochlea morphogenesisIEA
GO:0090190positive regulation of branching involved in ureteric bud morphogenesisISS
GO:0090191negative regulation of branching involved in ureteric bud morphogenesisIEA
GO:2000729positive regulation of mesenchymal cell proliferation involved in ureter developmentIEA
GO:0005667transcription factor complexISS
GO:0003677DNA bindingIDA
GO:0003682chromatin bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0003700sequence-specific DNA binding transcription factor activityISS
GO:0005515protein bindingIPI
GO:0043565sequence-specific DNA bindingIDA
GO:0044212transcription regulatory region DNA bindingIDA
GeneCards SIX1
UniProt Q15475
MIM 601205
HGNC 10887
HPRD 03125

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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