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Sequence in raw or FASTA format:

Database:

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WNK4 WNK lysine deficient protein kinase 4 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_032387 Homo sapiens WNK lysine deficient protein kinase 4 (WNK4), mRNA. ORF Sequence $1306.20
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Gene Symbol WNK4
Entrez Gene ID 65266
Full Name WNK lysine deficient protein kinase 4
Synonyms PHA2B, PRKWNK4
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q21-q22

Summary This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009].
Disorder

MIM: 601844

Pseudohypoaldosteronism type II, 145260 (3)

mRNA Protein Product Sequence Price Select
NM_032387, 260166636 NP_115763, 34365793 serine/threonine-protein kinase WNK4 Full Length $1467.90
ORF Sequence $1306.20
Homo sapiens (human)WNK4NP_115763.2
Pan troglodytes (chimpanzee)WNK4XP_003315535.1
Canis lupus familiaris (dog)WNK4XP_548082.3
Bos taurus (cattle)LOC100849076XP_003587489.1
Mus musculus (house mouse)Wnk4NP_783569.1
Rattus norvegicus (Norway rat)Wnk4NP_783169.2
Gallus gallus (chicken)LOC777580XP_003642875.1
Danio rerio (zebrafish)LOC557091XP_685164.3
Danio rerio (zebrafish)LOC100329810XP_002661200.2
Danio rerio (zebrafish)LOC100330953XP_002663933.2
GeneCards WNK4
PDB 2V3S
UniProt B0LPI0, Q96J92
MIM 601844
Ensembl ENSG00000126562
HGNC 14544
HPRD 03505

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
serine/threonine-protein kinase WNK4
Names
serine/threonine-protein kinase WNK4
protein kinase with no lysine 4
protein kinase lysine-deficient 4
NP_115763.2

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