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SNRPN small nuclear ribonucleoprotein polypeptide N [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu17081 NM_003097 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu17081 NM_022806 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 3, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu17081 NM_022808 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 5, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu17081 NM_022805 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu17081 NM_022807 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 4, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu17081C NM_003097 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00
OHu17081C NM_022806 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 3, mRNA. Customized vector In-stock 5-7 $149.00
OHu17081C NM_022808 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 5, mRNA. Customized vector In-stock 5-7 $149.00
OHu17081C NM_022805 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2, mRNA. Customized vector In-stock 5-7 $149.00
OHu17081C NM_022807 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 4, mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol SNRPN
Entrez Gene ID 6638
Full Name small nuclear ribonucleoprotein polypeptide N
Synonyms HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN, sm-N
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q11.2

Summary The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq, Jul 2008].
Disorder

MIM: 182279

Prader-Willi syndrome, 176270 (3)

mRNA Protein Product Sequence Price Select
NM_003097, 29540556 NP_003088, 4507135 small nuclear ribonucleoprotein-associated protein N ORF Sequence $159.00
NM_022805, 29540552 NP_073716, 13027644 small nuclear ribonucleoprotein-associated protein N ORF Sequence $159.00
NM_022806, 29540553 NP_073717, 13027646 small nuclear ribonucleoprotein-associated protein N ORF Sequence $159.00
NM_022807, 29540554 NP_073718, 13027648 small nuclear ribonucleoprotein-associated protein N ORF Sequence $159.00
NM_022808, 29540555 NP_073719, 13027650 small nuclear ribonucleoprotein-associated protein N ORF Sequence $159.00
WikiPathways
WP411mRNA processing
WP2363Gastric cancer network 2
Homo sapiens (human)SNRPNNP_003088.1
Pan troglodytes (chimpanzee)SNRPNNP_001243726.1
Macaca mulatta (Rhesus monkey)SNRPNXP_001108013.1
Canis lupus familiaris (dog)SNRPNXP_005618293.1
Bos taurus (cattle)SNRPNNP_001073265.1
Mus musculus (house mouse)SnrpnNP_001076430.1
Rattus norvegicus (Norway rat)SnrpnNP_112379.1
Gallus gallus (chicken)SNRPBNP_989930.1
Danio rerio (zebrafish)snrpbNP_991230.1
Drosophila melanogaster (fruit fly)SmBNP_001188780.1
Caenorhabditis eleganssnr-2NP_493348.1
Xenopus (Silurana) tropicalis (western clawed frog)snrpbNP_001001198.1
Process
IDNameEvidence
GO:0008380RNA splicingTAS
GO:0009725response to hormoneIEA
Component
IDNameEvidence
GO:0005681spliceosomal complexTAS
GO:0005685U1 snRNPIEA
GO:0005686U2 snRNPIEA
GO:0030532small nuclear ribonucleoprotein complexTAS
Function
IDNameEvidence
GO:0003723RNA bindingIEA
GO:0005515protein bindingIPI
GeneCards SNRPN
UniProt X5DP00, P63162
Vega OTTHUMG00000129180
MIM 182279
Ensembl ENSG00000128739
HGNC 11164
HPRD 01653

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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