Sequence in raw or FASTA format:
TNNC2 troponin C type 2 (fast) [Homo sapiens (human)]
| Gene Symbol | TNNC2 |
| Entrez Gene ID | 7125 |
| Full Name | troponin C type 2 (fast) |
| Synonyms | |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
20 20q12-q13.11 |
| Summary | Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq]. |
| Disorder | MIM: 191039 |
| mRNA | NM_003279, 40807466 |
| Protein | NP_003270, 4507617 |
| Product | troponin C, skeletal muscle |
| RefSeq Status | REVIEWED |
| hsa04020 | Calcium signaling pathway |
WikiPathways
| WP383 | Striated Muscle Contraction |
Reactome
| REACT_16969 | Striated Muscle Contraction |
| REACT_17044 | Muscle contraction |
| Homo sapiens (human) | TNNC2 | NP_003270.1 |
| Pan troglodytes (chimpanzee) | TNNC2 | XP_001157246.1 |
| Canis lupus familiaris (dog) | TNNC2 | XP_543023.2 |
| Mus musculus (house mouse) | Tnnc2 | NP_033420.1 |
| Rattus norvegicus (Norway rat) | Tnnc2 | NP_001032428.1 |
| Gallus gallus (chicken) | TNNC2 | NP_990781.1 |
| Danio rerio (zebrafish) | tnnc | NP_571638.1 |
| Danio rerio (zebrafish) | si:rp71-17i16.4 | XP_001339131.1 |
| ID | Name | Evidence |
| GO:0003009 | skeletal muscle contraction | IDA |
| GO:0006937 | regulation of muscle contraction | TAS |
| GO:0030049 | muscle filament sliding | TAS |
Component
| ID | Name | Evidence |
| GO:0005829 | cytosol | TAS |
| GO:0005861 | troponin complex | IDA |
Function
| ID | Name | Evidence |
| GO:0003779 | actin binding | IDA |
| GO:0005509 | calcium ion binding | IEA |
Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.
 |
Secured Online Quotation |
 |
Email: gene@genscript.com |
 |
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188 |
 |
Fax: 1-732-210-0262 1-732-885-5878 |