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TNNC2 troponin C type 2 (fast) [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu04113 NM_003279 Homo sapiens troponin C type 2 (fast) (TNNC2), mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu04113C NM_003279 Homo sapiens troponin C type 2 (fast) (TNNC2), mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol TNNC2
Entrez Gene ID 7125
Full Name troponin C type 2 (fast)
Synonyms
General protein information
Preferred Names
troponin C, skeletal muscle
Names
troponin C, skeletal muscle
troponin C2, fast
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

20

20q12-q13.11

Summary Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008].
Disorder

MIM: 191039

mRNA Protein Product Sequence Price Select
NM_003279, 40807466 NP_003270, 4507617 troponin C, skeletal muscle ORF Sequence $250.00
KEGG
hsa04020Calcium signaling pathway
WikiPathways
WP383Striated Muscle Contraction
Reactome
REACT_16969Striated Muscle Contraction
REACT_17044Muscle contraction
Homo sapiens (human)TNNC2NP_003270.1
Pan troglodytes (chimpanzee)TNNC2XP_001157246.1
Macaca mulatta (Rhesus monkey)TNNC2XP_001108623.1
Canis lupus familiaris (dog)TNNC2XP_543023.2
Bos taurus (cattle)TNNC2NP_001069841.1
Mus musculus (house mouse)Tnnc2NP_033420.1
Rattus norvegicus (Norway rat)Tnnc2NP_001032428.1
Gallus gallus (chicken)TNNC2NP_990781.1
Danio rerio (zebrafish)tnnc2NP_571638.1
Xenopus (Silurana) tropicalis (western clawed frog)tnnc2NP_988957.1
Process
IDNameEvidence
GO:0003009skeletal muscle contractionIDA
GO:0006937regulation of muscle contractionTAS
GO:0030049muscle filament slidingTAS
Component
IDNameEvidence
GO:0005829cytosolTAS
GO:0005861troponin complexIDA
Function
IDNameEvidence
GO:0003779actin bindingIDA
GO:0005509calcium ion bindingIEA
GeneCards TNNC2
UniProt P02585
Vega OTTHUMG00000032623
MIM 191039
Ensembl ENSG00000101470
HGNC 11944
HPRD 08929

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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