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WIPF1 WAS/WASL interacting protein family, member 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001077269 Homo sapiens WAS/WASL interacting protein family, member 1 (WIPF1), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_003387 Homo sapiens WAS/WASL interacting protein family, member 1 (WIPF1), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006712727 PREDICTED: Homo sapiens WAS/WASL interacting protein family, member 1 (WIPF1), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Related Services

Gene Symbol WIPF1
Entrez Gene ID 7456
Full Name WAS/WASL interacting protein family, member 1
Synonyms PRPL-2, WASPIP, WIP
General protein information
Preferred Names
WAS/WASL-interacting protein family member 1
Names
WAS/WASL-interacting protein family member 1
protein PRPL-2
WASP-interacting protein
Wiskott-Aldrich syndrome protein interacting protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q31.1

Summary This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602357

mRNA Protein Product Sequence Price Select
NM_001077269, 116284397 NP_001070737, 116284398 WAS/WASL-interacting protein family member 1 ORF Sequence $550.00
NM_003387, 116284399 NP_003378, 38373695 WAS/WASL-interacting protein family member 1 ORF Sequence $550.00
XM_006712727, 578804844 XP_006712790, 578804845 WAS/WASL-interacting protein family member 1 isoform X1 ORF Sequence $550.00
Pathway Interaction Database
fcer1pathwayFc-epsilon receptor I signaling in mast cells
Reactome
REACT_6802Innate Immune System
REACT_6900Immune System
REACT_160123Fcgamma receptor (FCGR) dependent phagocytosis
REACT_160086Regulation of actin dynamics for phagocytic cup formation
Homo sapiens (human)WIPF1NP_001070737.1
Pan troglodytes (chimpanzee)WIPF1XP_001150625.1
Macaca mulatta (Rhesus monkey)WIPF1XP_001090880.1
Canis lupus familiaris (dog)WIPF1XP_545531.3
Bos taurus (cattle)WIPF1NP_001070391.1
Mus musculus (house mouse)Wipf1NP_694778.1
Rattus norvegicus (Norway rat)Wipf1NP_476540.2
Gallus gallus (chicken)WIPF1NP_001012935.1
Process
IDNameEvidence
GO:0006461protein complex assemblyTAS
GO:0008154actin polymerization or depolymerizationIEA
GO:0030048actin filament-based movementIEA
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTAS
GO:0045087innate immune responseTAS
GO:0051707response to other organismIEA
Component
IDNameEvidence
GO:0001726ruffleIEA
GO:0005829cytosolTAS
GO:0005884actin filamentIEA
GO:0015629actin cytoskeletonTAS
GO:0016023cytoplasmic membrane-bounded vesicleIEA
Function
IDNameEvidence
GO:0003779actin bindingIEA
GO:0005515protein bindingIPI
GO:0005522profilin bindingTAS
GeneCards WIPF1
UniProt Q2YDC4, O43516
Vega OTTHUMG00000132334
MIM 602357
Ensembl ENSG00000115935
HGNC 12736
HPRD 03835

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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