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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_003401 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $549.00 14
NM_022406 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10
NM_022550 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $549.00 14

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Related Services

Gene Symbol XRCC4
Entrez Gene ID 7518
Full Name X-ray repair complementing defective repair in Chinese hamster cells 4
Synonyms
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q14.2

Summary The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008].
Disorder

MIM: 194363

mRNA Protein Product Sequence Price Select
NM_003401, 196162694 NP_003392, 4507945 DNA repair protein XRCC4 isoform 1 ORF Sequence $400.00
NM_022406, 196162693 NP_071801, 12408647 DNA repair protein XRCC4 isoform 2 ORF Sequence $269.00
NM_022550, 196162695 NP_072044, 12408649 DNA repair protein XRCC4 isoform 1 ORF Sequence $400.00
KEGG
hsa03450Non-homologous end-joining
WikiPathways
WP438Non-homologous end joining
Reactome
REACT_6185HIV Infection
REACT_116125Disease
REACT_6256HIV Life Cycle
REACT_6918Integration of provirus
REACT_90582-LTR circle formation
REACT_6266Early Phase of HIV Life Cycle
REACT_1022Nonhomologous End-joining (NHEJ)
REACT_2054Double-Strand Break Repair
REACT_216DNA Repair
Homo sapiens (human)XRCC4NP_071801.1
Pan troglodytes (chimpanzee)XRCC4XP_001148110.2
Macaca mulatta (Rhesus monkey)LOC712291XP_001111862.1
Canis lupus familiaris (dog)XRCC4XP_849518.1
Bos taurus (cattle)XRCC4NP_001075084.1
Mus musculus (house mouse)Xrcc4NP_082288.1
Rattus norvegicus (Norway rat)Xrcc4NP_001007000.1
Gallus gallus (chicken)XRCC4XP_424905.3
Danio rerio (zebrafish)xrcc4NP_957080.1
GeneCards XRCC4
PDB 3II6, 3Q4F, 3MUD, 3W03, 3SR2, 3RWR, 1FU1, 1IK9
UniProt Q13426, Q7Z763
MIM 194363
Ensembl ENSG00000152422
HGNC 12831
HPRD 15951

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
DNA repair protein XRCC4
Names
DNA repair protein XRCC4
X-ray repair cross-complementing protein 4
X-ray repair, complementing defective, repair in Chinese hamster

Interactant



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