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ULBP3 UL16 binding protein 3 [Homo sapiens (human)]


RefSeq Accession Definition Sequence Price Select
NM_024518 Homo sapiens UL16 binding protein 3 (ULBP3), mRNA. Full Length $213.15
ORF Sequence $213.15


Gene Symbol ULBP3
Entrez Gene ID 79465
Full Name UL16 binding protein 3
Synonyms RAET1N
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6q25
Summary
Disorder

MIM: 605699
mRNA NM_024518, 13375655
Protein NP_078794, 13375656
Product NKG2D ligand 3 precursor
RefSeq Status PROVISIONAL
KEGG
hsa04650Natural killer cell mediated cytotoxicity
Reactome
REACT_11152Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACT_6900Signaling in Immune system
Process
IDNameEvidence
GO:0002839positive regulation of immune response to tumor cellIEA
GO:0019882antigen processing and presentationIEA
GO:0030101natural killer cell activationNAS
GO:0032729positive regulation of interferon-gamma productionIEA
GO:0032816positive regulation of natural killer cell activationIEA
GO:0042271susceptibility to natural killer cell mediated cytotoxicityIEA
GO:0043032positive regulation of macrophage activationIEA
GO:0045429positive regulation of nitric oxide biosynthetic processIEA
GO:0050776regulation of immune responseTAS
Component
IDNameEvidence
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneIEA
GO:0009897external side of plasma membraneIEA
GO:0016020membraneNAS
GO:0031225anchored to membraneIEA
GO:0042612MHC class I protein complexIEA
Function
IDNameEvidence
GO:0032393MHC class I receptor activityNAS
GO:0046703natural killer cell lectin-like receptor bindingIEA
GeneCards ULBP3
PDB 1KCG
UniProt Q5VY82, Q9BZM4
MIM 605699
Ensembl ENSG00000131019
HGNC 14895
HPRD 16144

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