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RNASEH2B ribonuclease H2, subunit B [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001142279 Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $449.00 14
NM_024570 Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $449.00 14

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Related Services

Gene Symbol RNASEH2B
Entrez Gene ID 79621
Full Name ribonuclease H2, subunit B
Synonyms AGS2, DLEU8, FLJ11712
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

13

13q14.3

Summary RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008].
Disorder

MIM: 610326

Aicardi-Goutieres syndrome 2, 610181 (3)

mRNA Protein Product Sequence Price Select
NM_001142279, 326937470 NP_001135751, 214010191 ribonuclease H2 subunit B isoform 2 ORF Sequence $300.00
NM_024570, 326937471 NP_078846, 186910286 ribonuclease H2 subunit B isoform 1 ORF Sequence $300.00
KEGG
hsa03030DNA replication
Homo sapiens (human)RNASEH2BNP_078846.2
Pan troglodytes (chimpanzee)RNASEH2BXP_001158221.1
Macaca mulatta (Rhesus monkey)LOC707995XP_001105134.1
Canis lupus familiaris (dog)RNASEH2BXP_848995.1
Bos taurus (cattle)RNASEH2BNP_001160038.1
Mus musculus (house mouse)Rnaseh2bNP_080277.1
Rattus norvegicus (Norway rat)Rnaseh2bNP_001007008.1
Gallus gallus (chicken)RNASEH2BNP_001025997.1
Danio rerio (zebrafish)rnaseh2bNP_956565.1
Drosophila melanogaster (fruit fly)CG11164NP_572908.2
GeneCards RNASEH2B
PDB 3P87, 3PUF, 3P56
UniProt Q8N451, G3XAJ1, Q5TBB1
MIM 610326
Ensembl ENSG00000136104
HGNC 25671

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
ribonuclease H2 subunit B
Names
ribonuclease H2 subunit B
RNase H2 subunit B
ribonuclease HI subunit B
deleted in lymphocytic leukemia 8
Aicardi-Goutieres syndrome 2 protein

Interactant



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