• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


RNASEH2B ribonuclease H2, subunit B [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu23058 NM_001142279 Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu23224 NM_024570 Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu47264 XM_006719867 PREDICTED: Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu47265 XM_005266524 PREDICTED: Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu47266 XM_005266525 PREDICTED: Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu23058C NM_001142279 Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant 2, mRNA. Customized vector On-demand 7-9 $209.00
OHu23224C NM_024570 Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant 1, mRNA. Customized vector On-demand 7-9 $209.00
OHu47264C XM_006719867 PREDICTED: Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant X3, mRNA. Customized vector On-demand 7-9 $209.00
OHu47265C XM_005266524 PREDICTED: Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant X1, mRNA. Customized vector On-demand 7-9 $209.00
OHu47266C XM_005266525 PREDICTED: Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant X2, mRNA. Customized vector On-demand 7-9 $209.00

*Business Day

Related Services

Gene Symbol RNASEH2B
Entrez Gene ID 79621
Full Name ribonuclease H2, subunit B
Synonyms AGS2, DLEU8
General protein information
Preferred Names
ribonuclease H2 subunit B
Names
ribonuclease H2 subunit B
RNase H2 subunit B
ribonuclease HI subunit B
deleted in lymphocytic leukemia 8
Aicardi-Goutieres syndrome 2 protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

13

13q14.3

Summary RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008].
Disorder

MIM: 610326

Aicardi-Goutieres syndrome 2, 610181 (3)

mRNA Protein Product Sequence Price Select
NM_001142279, 326937470 NP_001135751, 214010191 ribonuclease H2 subunit B isoform 2 ORF Sequence $300.00
NM_024570, 326937471 NP_078846, 186910286 ribonuclease H2 subunit B isoform 1 ORF Sequence $300.00
XM_005266524, 530402643 XP_005266581, 530402644 ribonuclease H2 subunit B isoform X1 ORF Sequence $300.00
XM_005266525, 530402645 XP_005266582, 530402646 ribonuclease H2 subunit B isoform X2 ORF Sequence $300.00
XM_006719867, 578825006 XP_006719930, 578825007 ribonuclease H2 subunit B isoform X3 ORF Sequence $300.00
KEGG
hsa03030DNA replication
Homo sapiens (human)RNASEH2BNP_078846.2
Pan troglodytes (chimpanzee)RNASEH2BXP_001158221.1
Macaca mulatta (Rhesus monkey)LOC707995XP_001105134.1
Canis lupus familiaris (dog)LOC607281XP_005634133.1
Bos taurus (cattle)RNASEH2BNP_001160038.1
Mus musculus (house mouse)Rnaseh2bNP_080277.1
Rattus norvegicus (Norway rat)Rnaseh2bNP_001007008.1
Gallus gallus (chicken)RNASEH2BNP_001025997.1
Danio rerio (zebrafish)rnaseh2bNP_956565.1
Drosophila melanogaster (fruit fly)CG11164NP_572908.2
Xenopus (Silurana) tropicalis (western clawed frog)rnaseh2bNP_001016329.1
Process
IDNameEvidence
GO:0001701in utero embryonic developmentIEA
GO:0006401RNA catabolic processIDA
GO:0009259ribonucleotide metabolic processIEA
GO:0010389regulation of G2/M transition of mitotic cell cycleIEA
GO:0010629negative regulation of gene expressionIEA
GO:0048146positive regulation of fibroblast proliferationIEA
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolyticIEA
GO:2000001regulation of DNA damage checkpointIEA
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005730nucleolusIDA
GO:0032299ribonuclease H2 complexIDA
Function
IDNameEvidence
GO:0004523RNA-DNA hybrid ribonuclease activityIEA
GeneCards RNASEH2B
PDB 3P87, 3PUF, 3P56
UniProt Q8N451, Q5TBB1
Vega OTTHUMG00000016937
MIM 610326
Ensembl ENSG00000136104
HGNC 25671

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.