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MAFK v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_002360 Homo sapiens v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) (MAFK), mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10

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Gene Symbol MAFK
Entrez Gene ID 7975
Full Name v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
Synonyms FLJ32205, MGC71717, NFE2U, P18
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008].

MIM: 600197

mRNA Protein Product Sequence Price Select
NM_002360, 82617644 NP_002351, 4505075 transcription factor MafK ORF Sequence $159.00
REACT_24970Factors involved in megakaryocyte development and platelet production
Homo sapiens (human)MAFKNP_002351.1
Macaca mulatta (Rhesus monkey)LOC721769XP_001117972.1
Canis lupus familiaris (dog)LOC100856391XP_003639134.1
Bos taurus (cattle)MAFKNP_001193229.1
Mus musculus (house mouse)MafkNP_034887.1
Rattus norvegicus (Norway rat)MafkNP_663706.2
Gallus gallus (chicken)MAFKNP_990087.1
Danio rerio (zebrafish)mafkNP_001002044.2
Drosophila melanogaster (fruit fly)maf-SNP_611500.1
GeneCards MAFK
UniProt A4D214, O60675
MIM 600197
Ensembl ENSG00000198517
HGNC 6782
HPRD 02561

General protein information

Preferred Names
transcription factor MafK
transcription factor MafK
nuclear factor erythroid-2, ubiquitous (p18)
basic-leucine zipper transcription factor MafK
erythroid transcription factor NF-E2 p18 subunit
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K
v-maf avian musculoaponeurotic fibrosarcoma oncogene family, protein K


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