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CFHR5 complement factor H-related 5 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_030787 Homo sapiens complement factor H-related 5 (CFHR5), mRNA. GenEZ ORF Cloning On-demand $849.00 20

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Gene Symbol CFHR5
Entrez Gene ID 81494
Full Name complement factor H-related 5
Synonyms CFHL5, FHR-5, FHR5, FLJ10549, MGC133240
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010].

MIM: 608593

mRNA Protein Product Sequence Price Select
NM_030787, 164607154 NP_110414, 13540563 complement factor H-related protein 5 precursor ORF Sequence $700.00
Homo sapiens (human)CFHR5NP_110414.1
Pan troglodytes (chimpanzee)CFHR5XP_514078.3
Canis lupus familiaris (dog)CFHR5XP_547381.3
Bos taurus (cattle)CFHR5XP_003587159.1
GeneCards CFHR5
UniProt Q9BXR6
MIM 608593
Ensembl ENSG00000134389
HGNC 24668
HPRD 06508

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information


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