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AMN amnion associated transmembrane protein [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu18098D NM_030943 Homo sapiens amnion associated transmembrane protein (AMN), mRNA. pcDNA3.1-C-(k)DYK On-demand TBD Starting from $99
OHu18098C NM_030943 Homo sapiens amnion associated transmembrane protein (AMN), mRNA. Customized vector On-demand TBD Starting from $99

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Gene Symbol AMN
Entrez Gene ID 81693
Full Name amnion associated transmembrane protein
Synonyms PRO1028, amnionless
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008].

MIM: 605799

Megaloblastic anemia-1, Norwegian type, 261100 (3)

mRNA Protein Product Sequence Price Select
NM_030943, 189095273 NP_112205, 110611172 protein amnionless precursor ORF Sequence $550.00
REACT_13621HDL-mediated lipid transport
REACT_602Lipid digestion, mobilization, and transport
REACT_6823Lipoprotein metabolism
REACT_11238Metabolism of water-soluble vitamins and cofactors
REACT_11193Metabolism of vitamins and cofactors
REACT_22258Metabolism of lipids and lipoproteins
REACT_163862Cobalamin (Cbl, vitamin B12) transport and metabolism
REACT_169429Defects in cobalamin (B12) metabolism
REACT_169169Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
REACT_169120Defective TCN2 causes hereditary megaloblastic anemia
REACT_169318Defective MMAB causes methylmalonic aciduria type cblB
REACT_169256Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
REACT_169415Defective GIF causes intrinsic factor deficiency
REACT_169439Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169132Defective CUBN causes hereditary megaloblastic anemia 1
REACT_169280Defective AMN causes hereditary megaloblastic anemia 1
REACT_169313Defective MUT causes methylmalonic aciduria mut type
REACT_169312Defective HLCS causes multiple carboxylase deficiency
REACT_169363Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
REACT_169149Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169316Defective MMAA causes methylmalonic aciduria type cblA
REACT_169178Defective CD320 causes methylmalonic aciduria
REACT_169385Defects in vitamin and cofactor metabolism
REACT_169238Defects in biotin (Btn) metabolism
REACT_169403Defective BTD causes biotidinase deficiency
Homo sapiens (human)AMNNP_112205.2
Pan troglodytes (chimpanzee)AMNXP_510179.2
Bos taurus (cattle)AMNNP_001070509.1
Mus musculus (house mouse)AmnNP_291081.2
Rattus norvegicus (Norway rat)AmnNP_001101531.1
Gallus gallus (chicken)AMNNP_001264445.1
Danio rerio (zebrafish)amnXP_002661318.2
Xenopus (Silurana) tropicalis (western clawed frog)amnXP_002938043.1
GO:0006766vitamin metabolic processTAS
GO:0006767water-soluble vitamin metabolic processTAS
GO:0006898receptor-mediated endocytosisIDA
GO:0007275multicellular organismal developmentIEA
GO:0009235cobalamin metabolic processTAS
GO:0015889cobalamin transportIDA
GO:0042157lipoprotein metabolic processTAS
GO:0043001Golgi to plasma membrane protein transportIDA
GO:0044281small molecule metabolic processTAS
GO:0005615extracellular spaceIDA
GO:0005886plasma membraneTAS
GO:0010008endosome membraneTAS
GO:0016021integral component of membraneIEA
GO:0016324apical plasma membraneIDA
GO:0030139endocytic vesicleIDA
GO:0070062extracellular vesicular exosomeIDA
GO:0005102receptor bindingIPI
GeneCards AMN
UniProt Q9BXJ7
Vega OTTHUMG00000171897
MIM 605799
Ensembl ENSG00000166126
HGNC 14604
HPRD 09314

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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