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MADCAM1 mucosal vascular addressin cell adhesion molecule 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_130760 Homo sapiens mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_130762 Homo sapiens mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Related Services

Gene Symbol MADCAM1
Entrez Gene ID 8174
Full Name mucosal vascular addressin cell adhesion molecule 1
Synonyms MACAM1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.3

Summary The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008].
Disorder

MIM: 102670

mRNA Protein Product Sequence Price Select
NM_130760, 109633021 NP_570116, 109633022 mucosal addressin cell adhesion molecule 1 isoform a precursor ORF Sequence $400.00
NM_130762, 109633020 NP_570118, 18780285 mucosal addressin cell adhesion molecule 1 isoform b precursor ORF Sequence $300.00
KEGG
hsa04672Intestinal immune network for IgA production
hsa04514Cell adhesion molecules (CAMs)
Pathway Interaction Database
a4b1_paxindep_pathwayPaxillin-independent events mediated by a4b1 and a4b7
Reactome
REACT_6900Immune System
REACT_111102Signal Transduction
REACT_75774Adaptive Immune System
REACT_11152Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACT_13552Integrin cell surface interactions
Homo sapiens (human)MADCAM1NP_570116.2
Canis lupus familiaris (dog)MADCAM1NP_001019810.1
Bos taurus (cattle)MADCAM1NP_001032910.1
Mus musculus (house mouse)Madcam1NP_038619.2
Rattus norvegicus (Norway rat)Madcam1NP_062190.1
Gallus gallus (chicken)LOC100858236XP_003642914.1
GeneCards MADCAM1
PDB 4HC1, 1GSM, 1BQS, 4HD9, 4HBQ, 4HCR
UniProt Q5UGI7, Q13477
MIM 102670
Ensembl ENSG00000099866
HGNC 6765
HPRD 00035

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
mucosal addressin cell adhesion molecule 1
Names
mucosal addressin cell adhesion molecule 1
MAdCAM-1
hMAdCAM-1
mucosal addressin cell adhesion molecule-1

Interactant



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