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Sequence in raw or FASTA format:

Database:

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MADCAM1 mucosal vascular addressin cell adhesion molecule 1 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu13301 NM_130760 Homo sapiens mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu13360 NM_130762 Homo sapiens mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu13301C NM_130760 Homo sapiens mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 1, mRNA. Customized vector On-demand 7-9 $269.00
OHu13360C NM_130762 Homo sapiens mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 2, mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol MADCAM1
Entrez Gene ID 8174
Full Name mucosal vascular addressin cell adhesion molecule 1
Synonyms MACAM1
General protein information
Preferred Names
mucosal addressin cell adhesion molecule 1
Names
mucosal addressin cell adhesion molecule 1
MAdCAM-1
hMAdCAM-1
mucosal addressin cell adhesion molecule-1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.3

Summary The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008].
Disorder

MIM: 102670

mRNA Protein Product Sequence Price Select
NM_130760, 109633021 NP_570116, 109633022 mucosal addressin cell adhesion molecule 1 isoform a precursor ORF Sequence $400.00
NM_130762, 109633020 NP_570118, 18780285 mucosal addressin cell adhesion molecule 1 isoform b precursor ORF Sequence $300.00
KEGG
hsa04514Cell adhesion molecules (CAMs)
hsa04672Intestinal immune network for IgA production
Pathway Interaction Database
a4b1_paxindep_pathwayPaxillin-independent events mediated by a4b1 and a4b7
Reactome
REACT_13552Integrin cell surface interactions
REACT_6900Immune System
REACT_11152Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACT_75774Adaptive Immune System
REACT_118779Extracellular matrix organization
Process
IDNameEvidence
GO:0002687positive regulation of leukocyte migrationIEA
GO:0006955immune responseTAS
GO:0007155cell adhesionIEA
GO:0007165signal transductionTAS
GO:0007568agingIEA
GO:0009790embryo developmentIEA
GO:0030198extracellular matrix organizationTAS
GO:0030216keratinocyte differentiationIEA
GO:0050776regulation of immune responseTAS
GO:0050900leukocyte migrationIEA
Component
IDNameEvidence
GO:0005886plasma membraneTAS
GO:0016020membraneTAS
GO:0016021integral component of membraneIEA
GeneCards MADCAM1
UniProt Q13477
Vega OTTHUMG00000180548
MIM 102670
Ensembl ENSG00000099866
HGNC 6765
HPRD 00035

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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