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ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_030957 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), mRNA. ORF Sequence $1159.20
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Gene Symbol ADAMTS10
Entrez Gene ID 81794
Full Name ADAM metallopeptidase with thrombospondin type 1 motif, 10
Synonyms ADAM-TS10, WMS
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.2

Summary This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008].
Disorder

MIM: 608990

Weill-Marchesani syndrome, recessive, 277600 (3)

mRNA Protein Product Sequence Price Select
NM_030957, 56121814 NP_112219, 56121815 A disintegrin and metalloproteinase with thrombospondin motifs 10 preproprotein Full Length $1482.95
ORF Sequence $1159.20
Homo sapiens (human)ADAMTS10NP_112219.2
Pan troglodytes (chimpanzee)ADAMTS10XP_001159753.1
Macaca mulatta (Rhesus monkey)ADAMTS10XP_001095103.1
Canis lupus familiaris (dog)ADAMTS10XP_854320.1
Bos taurus (cattle)ADAMTS10NP_001192679.1
Mus musculus (house mouse)Adamts10NP_766207.2
Rattus norvegicus (Norway rat)Adamts10NP_001030102.1
Gallus gallus (chicken)ADAMTS10XP_001232250.1
Danio rerio (zebrafish)adamts10NP_001116746.1
GeneCards ADAMTS10
UniProt Q9H324, Q6ZN14
MIM 608990
Ensembl ENSG00000142303
HGNC 13201
HPRD 07470

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Interactant

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