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ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu20510 NM_030957 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu20533 NM_001282352 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu20510 XM_006722916 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu51850 XM_006722917 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu51851 XM_005272499 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu51852 XM_005272500 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu20510C NM_030957 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant 1, mRNA. Customized vector On-demand 25 $1699.00
OHu20533C NM_001282352 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00
OHu20510C XM_006722916 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X4, mRNA. Customized vector On-demand 25 $1699.00
OHu51850C XM_006722917 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X5, mRNA. Customized vector On-demand 12-14 $329.00
OHu51851C XM_005272499 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X2, mRNA. Customized vector On-demand 7-9 $269.00
OHu51852C XM_005272500 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X3, mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol ADAMTS10
Entrez Gene ID 81794
Full Name ADAM metallopeptidase with thrombospondin type 1 motif, 10
Synonyms ADAM-TS10, ADAMTS-10, WMS, WMS1
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.2

Summary This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008].
Disorder

MIM: 608990

Weill-Marchesani syndrome, recessive, 277600 (3)

mRNA Protein Product Sequence Price Select
NM_001282352, 537544567 NP_001269281, 537544568 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 2 ORF Sequence $700.00
NM_030957, 537544565 NP_112219, 537544566 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein ORF Sequence $1500.00
XM_005272499, 530427544 XP_005272556, 530427545 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X2 ORF Sequence $700.00
XM_005272500, 530427546 XP_005272557, 530427547 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X3 ORF Sequence $700.00
XM_006722916, 578833666 XP_006722979, 578833667 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X4 ORF Sequence $1500.00
XM_006722917, 578833668 XP_006722980, 578833669 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X5 ORF Sequence $750.00
Reactome
REACT_17015Metabolism of proteins
REACT_22161Post-translational protein modification
REACT_200727O-linked glycosylation
REACT_200626O-glycosylation of TSR domain-containing proteins
Homo sapiens (human)ADAMTS10NP_112219.3
Pan troglodytes (chimpanzee)ADAMTS10XP_001159753.1
Macaca mulatta (Rhesus monkey)ADAMTS10XP_001095217.1
Canis lupus familiaris (dog)ADAMTS10XP_854320.1
Bos taurus (cattle)ADAMTS10NP_001192679.1
Mus musculus (house mouse)Adamts10NP_766207.2
Rattus norvegicus (Norway rat)Adamts10NP_001258374.1
Gallus gallus (chicken)ADAMTS10XP_001232250.1
Danio rerio (zebrafish)adamts10NP_001116746.1
Xenopus (Silurana) tropicalis (western clawed frog)adamts10XP_002938612.2
Process
IDNameEvidence
GO:0006508proteolysisIEA
GO:0008150biological_processND
Component
IDNameEvidence
GO:0001527microfibrilIDA
GO:0031012extracellular matrixIDA
Function
IDNameEvidence
GO:0003674molecular_functionND
GO:0004222metalloendopeptidase activityIEA
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GeneCards ADAMTS10
UniProt Q59FE5, Q9H324, Q6ZN14
Vega OTTHUMG00000182216
MIM 608990
Ensembl ENSG00000142303
HGNC 13201
HPRD 07470

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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