• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001282352 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $849.00 20
NM_030957 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005272499 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $849.00 20
XM_005272500 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $849.00 20
XM_006722916 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_006722917 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X5, mRNA. GenEZ ORF Cloning On-demand $899.00 20

*Business Day

Related Services

Gene Symbol ADAMTS10
Entrez Gene ID 81794
Full Name ADAM metallopeptidase with thrombospondin type 1 motif, 10
Synonyms ADAM-TS10, ADAMTS-10, WMS, WMS1
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.2

Summary This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008].
Disorder

MIM: 608990

Weill-Marchesani syndrome, recessive, 277600 (3)

mRNA Protein Product Sequence Price Select
NM_001282352, 537544567 NP_001269281, 537544568 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 2 ORF Sequence $700.00
NM_030957, 537544565 NP_112219, 537544566 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein ORF Sequence $1500.00
XM_005272499, 530427544 XP_005272556, 530427545 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X2 ORF Sequence $700.00
XM_005272500, 530427546 XP_005272557, 530427547 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X3 ORF Sequence $700.00
XM_006722916, 578833666 XP_006722979, 578833667 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X4 ORF Sequence $1500.00
XM_006722917, 578833668 XP_006722980, 578833669 A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X5 ORF Sequence $750.00
Reactome
REACT_17015Metabolism of proteins
REACT_22161Post-translational protein modification
REACT_200727O-linked glycosylation
REACT_200626O-glycosylation of TSR domain-containing proteins
Homo sapiens (human)ADAMTS10NP_112219.3
Pan troglodytes (chimpanzee)ADAMTS10XP_001159753.1
Macaca mulatta (Rhesus monkey)ADAMTS10XP_001095217.1
Canis lupus familiaris (dog)ADAMTS10XP_854320.1
Bos taurus (cattle)ADAMTS10NP_001192679.1
Mus musculus (house mouse)Adamts10NP_766207.2
Rattus norvegicus (Norway rat)Adamts10NP_001258374.1
Gallus gallus (chicken)ADAMTS10XP_001232250.1
Danio rerio (zebrafish)adamts10NP_001116746.1
Xenopus (Silurana) tropicalis (western clawed frog)adamts10XP_002938612.2
Process
IDNameEvidence
GO:0006508proteolysisIEA
GO:0008150biological_processND
Component
IDNameEvidence
GO:0001527microfibrilIDA
GO:0031012extracellular matrixIDA
Function
IDNameEvidence
GO:0003674molecular_functionND
GO:0004222metalloendopeptidase activityIEA
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GeneCards ADAMTS10
UniProt Q59FE5, Q9H324, Q6ZN14
Vega OTTHUMG00000182216
MIM 608990
Ensembl ENSG00000142303
HGNC 13201
HPRD 07470

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the ADAMTS10 gene?

The ADAMTS10 gene provides instructions for making an enzyme that is found in many of the body's cells and tissues. This enzyme is part of a family of metalloproteases, which are zinc-containing enzymes that cut apart other proteins. Although the function of the ADAMTS10 enzyme is unknown, it is critical for growth before and after birth. Researchers believe that it may be involved in the development of structures including the skin, eyes, heart, and skeleton.

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.