Sequence in raw or FASTA format:
USP9Y ubiquitin specific peptidase 9, Y-linked [Homo sapiens (human)]
|Entrez Gene ID||8287|
|Full Name||ubiquitin specific peptidase 9, Y-linked|
|General protein information||
|Organism||Homo sapiens (human)|
|Summary||This gene is a member of the peptidase C19 family. It encodes a protein that is similar to ubiquitin-specific proteases, which cleave the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. [provided by RefSeq, Mar 2009].|
Azoospermia, 415000 (3)
|Homo sapiens (human)||USP9Y||NP_004645.2|
|Bos taurus (cattle)||USP9Y||NP_001138981.1|
|Mus musculus (house mouse)||Usp9y||NP_683745.2|
|GO:0006511||ubiquitin-dependent protein catabolic process||IEA|
|GO:0007179||transforming growth factor beta receptor signaling pathway||ISS|
|GO:0030509||BMP signaling pathway||ISS|
|GO:0004843||ubiquitin-specific protease activity||TAS|
|GO:0008234||cysteine-type peptidase activity||TAS|
What is the normal function of the USP9Y gene?
The USP9Y gene provides instructions for making a protein called ubiquitin-specific protease 9. This gene is found on the Y chromosome. People normally have 46 chromosomes in each cell. Two of the 46 chromosomes are sex chromosomes, called X and Y. Females have two X chromosomes (46,XX), and males have one X chromosome and one Y chromosome (46,XY).
Because it is located on the Y chromosome, the USP9Y gene is present only in males. It occurs in a region of the Y chromosome called azoospermia factor A (AZFA). Azoospermia is the absence of sperm cells. The USP9Y gene is believed to be involved in sperm cell development, but its specific function is not well understood.
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