Sequence in raw or FASTA format:
USP9Y ubiquitin specific peptidase 9, Y-linked [Homo sapiens (human)]
| Gene Symbol | USP9Y |
| Entrez Gene ID | 8287 |
| Full Name | ubiquitin specific peptidase 9, Y-linked |
| Synonyms | DFFRY, FLJ33043 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
Y Yq11.2 |
| Summary | This gene is a member of the peptidase C19 family. It encodes a protein that is similar to ubiquitin-specific proteases, which cleave the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. [provided by RefSeq]. |
| Disorder | MIM: 400005 Azoospermia, 415000 (3) |
| mRNA | NM_004654, 74319832 |
| Protein | NP_004645, 74319833 |
| Product | probable ubiquitin carboxyl-terminal hydrolase FAF-Y |
| RefSeq Status | REVIEWED |
| Homo sapiens (human) | USP9Y | NP_004645.2 |
| Mus musculus (house mouse) | Usp9y | NP_683745.2 |
| ID | Name | Evidence |
| GO:0006511 | ubiquitin-dependent protein catabolic process | IEA |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | ISS |
| GO:0007283 | spermatogenesis | TAS |
| GO:0016579 | protein deubiquitination | ISS |
| GO:0030509 | BMP signaling pathway | ISS |
Component
| ID | Name | Evidence |
| GO:0005737 | cytoplasm | ISS |
Function
| ID | Name | Evidence |
| GO:0004221 | ubiquitin thiolesterase activity | IEA |
| GO:0004843 | ubiquitin-specific protease activity | TAS |
| GO:0005488 | binding | IEA |
| GO:0008233 | peptidase activity | IEA |
| GO:0008234 | cysteine-type peptidase activity | IEA |
| GO:0070410 | co-SMAD binding | ISS |
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