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USP9Y ubiquitin specific peptidase 9, Y-linked [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_004654 Homo sapiens ubiquitin specific peptidase 9, Y-linked (USP9Y), mRNA. GenEZ ORF Cloning On-demand $3749.00 35

*Business Day

Related Services

Gene Symbol USP9Y
Entrez Gene ID 8287
Full Name ubiquitin specific peptidase 9, Y-linked
Synonyms DFFRY, SPGFY2
General protein information
Preferred Names
probable ubiquitin carboxyl-terminal hydrolase FAF-Y
Names
probable ubiquitin carboxyl-terminal hydrolase FAF-Y
ubiquitin thioesterase FAF-Y
deubiquitinating enzyme FAF-Y
ubiquitin thiolesterase FAF-Y
fat facets protein-related, Y-linked
ubiquitin-specific protease 9, Y chromosome
ubiquitin-specific processing protease FAF-Y
ubiquitin-specific-processing protease FAF-Y
ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila)
NP_004645.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

Y

Yq11.2

Summary This gene is a member of the peptidase C19 family. It encodes a protein that is similar to ubiquitin-specific proteases, which cleave the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. [provided by RefSeq, Mar 2009].
Disorder

MIM: 400005

Azoospermia, 415000 (3)

mRNA Protein Product Sequence Price Select
NM_004654, 74319832 NP_004645, 74319833 probable ubiquitin carboxyl-terminal hydrolase FAF-Y ORF Sequence $3500.00
Homo sapiens (human)USP9YNP_004645.2
Bos taurus (cattle)USP9YNP_001138981.1
Mus musculus (house mouse)Usp9yNP_683745.2
Process
IDNameEvidence
GO:0006511ubiquitin-dependent protein catabolic processIEA
GO:0007179transforming growth factor beta receptor signaling pathwayISS
GO:0007283spermatogenesisTAS
GO:0016579protein deubiquitinationISS
GO:0030509BMP signaling pathwayISS
Component
IDNameEvidence
GO:0005737cytoplasmISS
Function
IDNameEvidence
GO:0004843ubiquitin-specific protease activityTAS
GO:0008234cysteine-type peptidase activityTAS
GO:0070410co-SMAD bindingISS
GeneCards USP9Y
UniProt O00507
Vega OTTHUMG00000036469
MIM 400005
Ensembl ENSG00000114374
HGNC 12633
HPRD 02449

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the USP9Y gene?

The USP9Y gene provides instructions for making a protein called ubiquitin-specific protease 9. This gene is found on the Y chromosome. People normally have 46 chromosomes in each cell. Two of the 46 chromosomes are sex chromosomes, called X and Y. Females have two X chromosomes (46,XX), and males have one X chromosome and one Y chromosome (46,XY).

Because it is located on the Y chromosome, the USP9Y gene is present only in males. It occurs in a region of the Y chromosome called azoospermia factor A (AZFA). Azoospermia is the absence of sperm cells. The USP9Y gene is believed to be involved in sperm cell development, but its specific function is not well understood.

Interactant

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