HIST1H2BG histone cluster 1, H2bg [Homo sapiens (human)]
| Gene Symbol | HIST1H2BG |
| Entrez Gene ID | 8339 |
| Full Name | histone cluster 1, H2bg |
| Synonyms | H2B.1A, H2B/a, H2B/g, H2B/h, H2B/k, H2B/l, H2BFA, dJ221C16.8 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
6 6p21.3 |
| Summary | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq]. |
| Disorder | MIM: 602798 |
| mRNA | NM_003518, 21536482 |
| Protein | NP_003509, 4504257 |
| Product | histone H2B type 1-C/E/F/G/I |
| RefSeq Status | REVIEWED |
| hsa05322 | Systemic lupus erythematosus |
Reactome
| REACT_7963 | Packaging Of Telomere Ends |
| REACT_21352 | RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription |
| REACT_1309 | RNA Polymerase I Transcription |
| REACT_22186 | Deposition of New CENPA-containing Nucleosomes at the Centromere |
| REACT_2204 | RNA Polymerase I Chain Elongation |
| REACT_2232 | RNA Polymerase I Promoter Opening |
| REACT_1788 | Transcription |
| REACT_7970 | Telomere Maintenance |
| REACT_22344 | Nucleosome assembly |
| REACT_1974 | RNA Polymerase I Promoter Clearance |
| REACT_22172 | Chromosome Maintenance |
| Homo sapiens (human) | HIST1H2BG | NP_003509.1 |
| Homo sapiens (human) | HIST2H2BE | NP_003519.1 |
| Homo sapiens (human) | HIST1H2BI | NP_003516.1 |
| Homo sapiens (human) | HIST1H2BC | NP_003517.2 |
| Homo sapiens (human) | HIST1H2BF | NP_003513.1 |
| Homo sapiens (human) | HIST1H2BE | NP_003514.2 |
| Pan troglodytes (chimpanzee) | LOC471902 | XP_527280.2 |
| Canis lupus familiaris (dog) | LOC608682 | XP_859568.1 |
| Canis lupus familiaris (dog) | LOC483169 | XP_540287.1 |
| Canis lupus familiaris (dog) | LOC483173 | XP_540291.1 |
| Canis lupus familiaris (dog) | LOC483170 | XP_540288.1 |
| Canis lupus familiaris (dog) | LOC488267 | XP_545389.1 |
| Canis lupus familiaris (dog) | LOC478743 | XP_848229.1 |
| Canis lupus familiaris (dog) | LOC488276 | XP_545398.2 |
| Canis lupus familiaris (dog) | LOC488296 | XP_545418.1 |
| Canis lupus familiaris (dog) | LOC611126 | XP_853860.1 |
| Canis lupus familiaris (dog) | LOC611465 | XP_854227.1 |
| Canis lupus familiaris (dog) | LOC611482 | XP_854244.1 |
| Bos taurus (cattle) | LOC529646 | XP_608099.1 |
| Mus musculus (house mouse) | Hist1h2bn | NP_835508.1 |
| Mus musculus (house mouse) | Hist1h2bk | NP_783596.1 |
| Mus musculus (house mouse) | Hist1h2bl | NP_835506.1 |
| Mus musculus (house mouse) | Hist1h2bf | NP_835502.1 |
| Mus musculus (house mouse) | Hist1h2bj | NP_835505.1 |
| Rattus norvegicus (Norway rat) | Hist1h2bf | XP_225384.1 |
| Gallus gallus (chicken) | H2B-V | XP_416197.2 |
| Gallus gallus (chicken) | LOC769845 | XP_001232871.1 |
| Gallus gallus (chicken) | LOC770267 | XP_001233337.1 |
| Gallus gallus (chicken) | LOC769973 | XP_001232985.1 |
| Gallus gallus (chicken) | LOC770188 | XP_001233227.1 |
| Gallus gallus (chicken) | H2B-VII | XP_416196.2 |
| Danio rerio (zebrafish) | hist2h2l | NP_956411.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33910 | NP_001027283.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG17949 | NP_724342.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33908 | NP_001027287.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33906 | NP_001027291.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33904 | NP_001027296.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33902 | NP_001027300.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33900 | NP_001027305.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33898 | NP_001027310.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33896 | NP_001027315.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33894 | NP_001027320.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33892 | NP_001027325.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33890 | NP_001027330.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33888 | NP_001027335.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33886 | NP_001027340.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33884 | NP_001027345.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33882 | NP_001027350.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33880 | NP_001027355.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33878 | NP_001027360.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33876 | NP_001027365.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33874 | NP_001027370.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33872 | NP_001027375.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33870 | NP_001027380.1 |
| Drosophila melanogaster (fruit fly) | His2B:CG33868 | NP_001027385.1 |
| Arabidopsis thaliana (thale cress) | HTB2 | NP_197679.1 |
| Arabidopsis thaliana (thale cress) | HTB1 | NP_172258.1 |
| Arabidopsis thaliana (thale cress) | HTB9 | NP_190184.1 |
| Arabidopsis thaliana (thale cress) | AT2G28720 | NP_180440.1 |
| Arabidopsis thaliana (thale cress) | HTB4 | NP_200799.1 |
| Arabidopsis thaliana (thale cress) | HTB11 | NP_190189.1 |
| GeneCards | HIST1H2BG |
| MIM | 602798 |
| Ensembl | ENSG00000187990 |
| HGNC | 4746 |
| HPRD | 11897 |
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