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HIST1H2BE histone cluster 1, H2be [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_003523 Homo sapiens histone cluster 1, H2be (HIST1H2BE), mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10

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Gene Symbol HIST1H2BE
Entrez Gene ID 8344
Full Name histone cluster 1, H2be
Synonyms H2B.h, H2B/h, H2BFH, dJ221C16.8
General protein information
Preferred Names
histone H2B type 1-C/E/F/G/I
Names
histone H2B type 1-C/E/F/G/I
histone H2B.h
histone 1, H2be
histone H2B.1 A
H2B histone family, member H
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p22.1

Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602805

mRNA Protein Product Sequence Price Select
NM_003523, 21396483 NP_003514, 21396484 histone H2B type 1-C/E/F/G/I ORF Sequence $99.00
KEGG
hsa05322Systemic lupus erythematosus
hsa05034Alcoholism
hsa05203Viral carcinogenesis
Reactome
REACT_152Cell Cycle, Mitotic
REACT_765Mitotic Prophase
REACT_910M Phase
REACT_71Gene Expression
REACT_11045Signaling by Wnt
REACT_1974RNA Polymerase I Promoter Clearance
REACT_7970Telomere Maintenance
REACT_2204RNA Polymerase I Chain Elongation
REACT_2232RNA Polymerase I Promoter Opening
REACT_7963Packaging Of Telomere Ends
REACT_1309RNA Polymerase I Transcription
REACT_22344Nucleosome assembly
REACT_21352RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
REACT_22186Deposition of new CENPA-containing nucleosomes at the centromere
REACT_22172Chromosome Maintenance
REACT_27271Meiotic recombination
REACT_75925Amyloids
REACT_111183Meiosis
REACT_75792Meiotic synapsis
REACT_111102Signal Transduction
REACT_116125Disease
REACT_115566Cell Cycle
REACT_120956Cellular responses to stress
REACT_169274Cellular Senescence
REACT_169168Senescence-Associated Secretory Phenotype (SASP)
REACT_169436Oxidative Stress Induced Senescence
REACT_169185DNA Damage/Telomere Stress Induced Senescence
REACT_200808PRC2 methylates histones and DNA
REACT_200834Negative epigenetic regulation of rRNA expression
REACT_200827SIRT1 negatively regulates rRNA Expression
REACT_200857Epigenetic regulation of gene expression
REACT_200777TCF dependent signaling in response to WNT
REACT_200856NoRC negatively regulates rRNA expression
REACT_200753formation of the beta-catenin:TCF transactivating complex
REACT_172633Chromatin modifying enzymes
REACT_172610HATs acetylate histones
REACT_172744Condensation of Prophase Chromosomes
REACT_172623Chromatin organization
Homo sapiens (human)HIST1H2BENP_003514.2
Pan troglodytes (chimpanzee)LOC471883XP_527261.1
Canis lupus familiaris (dog)LOC100856116XP_003640206.1
Bos taurus (cattle)HIST1H2BLXP_002686101.1
Mus musculus (house mouse)Hist1h2blNP_835506.1
GeneCards HIST1H2BE
Vega OTTHUMG00000014427
MIM 602805
Ensembl ENSG00000197697
HGNC 4753
HPRD 11901

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