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MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001013836 Homo sapiens MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $639.00 $590.00 15
NM_001013837 Homo sapiens MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 3, mRNA. GenEZ ORF Cloning In-stock $639.00 $590.00 15
NM_003550 Homo sapiens MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $639.00 $590.00 15

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Gene Symbol MAD1L1
Entrez Gene ID 8379
Full Name MAD1 mitotic arrest deficient-like 1 (yeast)
Synonyms MAD1, PIG9, TP53I9, TXBP181
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7p22

Summary MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602686

Lymphoma, somatic (3); Prostate cancer, somatic, 176807 (3)

mRNA Protein Product Sequence Price Select
NM_001013836, 62243368 NP_001013858, 62243369 mitotic spindle assembly checkpoint protein MAD1 ORF Sequence $490.00
NM_001013837, 62243373 NP_001013859, 62243374 mitotic spindle assembly checkpoint protein MAD1 ORF Sequence $490.00
NM_003550, 62243331 NP_003541, 62243332 mitotic spindle assembly checkpoint protein MAD1 ORF Sequence $490.00
KEGG
hsa04110Cell cycle
hsa04914Progesterone-mediated oocyte maturation
hsa05203Viral carcinogenesis
WikiPathways
WP179Cell cycle
Pathway Interaction Database
cmyb_pathwayC-MYB transcription factor network
Reactome
REACT_795Amplification of signal from the kinetochores
REACT_152Cell Cycle, Mitotic
REACT_682Mitotic Prometaphase
REACT_21300Mitotic M-M/G1 phases
REACT_115566Cell Cycle
REACT_383DNA Replication
REACT_491Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
REACT_1538Cell Cycle Checkpoints
REACT_2137Mitotic Spindle Checkpoint
REACT_910M Phase
Homo sapiens (human)MAD1L1NP_001013858.1
Pan troglodytes (chimpanzee)MAD1L1XP_003318259.1
Macaca mulatta (Rhesus monkey)MAD1L1XP_001102100.1
Canis lupus familiaris (dog)MAD1L1XP_852066.2
Bos taurus (cattle)MAD1L1NP_001095514.1
Mus musculus (house mouse)Mad1l1NP_034882.2
Rattus norvegicus (Norway rat)Mad1l1NP_001102857.1
Gallus gallus (chicken)MAD1L1XP_425231.2
Danio rerio (zebrafish)mad1l1NP_957206.2
Drosophila melanogaster (fruit fly)Mad1NP_610477.2
Arabidopsis thaliana (thale cress)AT5G49880NP_199799.1
GeneCards MAD1L1
PDB 1GO4, 4DZO
UniProt Q9Y6D9
MIM 602686
Ensembl ENSG00000002822
HGNC 6762
HPRD 04065

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
mitotic spindle assembly checkpoint protein MAD1
Names
mitotic spindle assembly checkpoint protein MAD1
MAD1-like protein 1
tax-binding protein 181
tumor protein p53 inducible protein 9
mitotic checkpoint MAD1 protein homolog
mitotic arrest deficient 1-like protein 1
mitotic-arrest deficient 1, yeast, homolog-like 1

Interactant



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