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Sequence in raw or FASTA format:


Blast Method:


MAGT1 magnesium transporter 1 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_032121 Homo sapiens magnesium transporter 1 (MAGT1), mRNA. GenEZ ORF Cloning On-demand $549.00 14

*Business Day

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Gene Symbol MAGT1
Entrez Gene ID 84061
Full Name magnesium transporter 1
Synonyms IAP, MRX95, OST3B, PRO0756, XMEN, bA217H1.1
General protein information
Preferred Names
magnesium transporter protein 1
magnesium transporter protein 1
implantation-associated protein
oligosaccharyltransferase 3 homolog B
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jan 2010].

MIM: 300715

Mental retardation, X-linked 95, 300716 (3)

mRNA Protein Product Sequence Price Select
NM_032121, 215983057 NP_115497, 215983058 magnesium transporter protein 1 ORF Sequence $400.00
REACT_17015Metabolism of proteins
REACT_22161Post-translational protein modification
REACT_22426Asparagine N-linked glycosylation
Homo sapiens (human)MAGT1NP_115497.4
Macaca mulatta (Rhesus monkey)LOC710098XP_002806337.1
Canis lupus familiaris (dog)MAGT1XP_549095.3
Bos taurus (cattle)MAGT1NP_001231247.1
Mus musculus (house mouse)Magt1NP_001177338.1
Rattus norvegicus (Norway rat)Magt1NP_446398.1
Gallus gallus (chicken)MAGT1NP_001006435.1
Danio rerio (zebrafish)magt1NP_955994.1
Xenopus (Silurana) tropicalis (western clawed frog)magt1XP_002931857.1
GO:0006487protein N-linked glycosylationNAS
GO:0015693magnesium ion transportIMP
GO:0018279protein N-linked glycosylation via asparagineTAS
GO:0043687post-translational protein modificationTAS
GO:0044267cellular protein metabolic processTAS
GO:0005789endoplasmic reticulum membraneTAS
GO:0005887integral component of plasma membraneNAS
GO:0008250oligosaccharyltransferase complexIDA
GO:0015095magnesium ion transmembrane transporter activityIMP
GeneCards MAGT1
UniProt Q9H0U3
Vega OTTHUMG00000021882
MIM 300715
Ensembl ENSG00000102158
HGNC 28880
HPRD 06487

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the MAGT1 gene?

The MAGT1 gene provides instructions for making a protein called a magnesium transporter, which moves charged atoms (ions) of magnesium (Mg2+) into certain immune system cells called T cells. T cells recognize foreign invaders, such as viruses, bacteria, and fungi, and are then turned on (activated) to attack these invaders in order to prevent infection and illness. Specifically, the magnesium transporter produced from the MAGT1 gene is active in CD8+ T cells, which are especially important in controlling viral infections such as the Epstein-Barr virus (EBV). These cells normally take in magnesium when they detect a foreign invader, and the magnesium is involved in activating the T cell's response.

Researchers suggest that magnesium transport may also be involved in the production of another type of T cell called helper T cells (CD4+ T cells) in a gland called the thymus. CD4+ T cells direct and assist the functions of the immune system by influencing the activities of other immune system cells.


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