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MAF1 MAF1 homolog (S. cerevisiae) [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu30790 NM_032272 Homo sapiens MAF1 homolog (S. cerevisiae) (MAF1), mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu30790C NM_032272 Homo sapiens MAF1 homolog (S. cerevisiae) (MAF1), mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol MAF1
Entrez Gene ID 84232
Full Name MAF1 homolog (S. cerevisiae)
Synonyms
General protein information
Preferred Names
repressor of RNA polymerase III transcription MAF1 homolog
Names
repressor of RNA polymerase III transcription MAF1 homolog
homolog of yeast MAF1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8q24.3

Summary This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008].
Disorder

MIM: 610210

mRNA Protein Product Sequence Price Select
NM_032272, 110349739 NP_115648, 110349740 repressor of RNA polymerase III transcription MAF1 homolog ORF Sequence $300.00
Homo sapiens (human)MAF1NP_115648.2
Pan troglodytes (chimpanzee)MAF1XP_001155989.2
Macaca mulatta (Rhesus monkey)MAF1XP_001089551.1
Canis lupus familiaris (dog)MAF1XP_005628130.1
Bos taurus (cattle)MAF1NP_001029596.1
Mus musculus (house mouse)Maf1NP_001158079.1
Rattus norvegicus (Norway rat)Maf1NP_001014107.1
Gallus gallus (chicken)MAF1XP_003643589.2
Danio rerio (zebrafish)maf1NP_998606.1
Drosophila melanogaster (fruit fly)Maf1NP_001015167.2
Caenorhabditis elegansC43H8.2NP_492777.1
Arabidopsis thaliana (thale cress)AT5G13240NP_196828.2
Process
IDNameEvidence
GO:0006351transcription, DNA-templatedIEA
GO:0016480negative regulation of transcription from RNA polymerase III promoterIDA
Component
IDNameEvidence
GO:0005622intracellularIDA
GO:0005634nucleusIDA
GO:0005737cytoplasmIDA
GO:0005829cytosolIEA
GO:0005886plasma membraneIEA
GO:0030424axonIEA
GO:0030425dendriteIEA
GO:0060077inhibitory synapseIEA
Function
IDNameEvidence
GO:0001030RNA polymerase III type 1 promoter DNA bindingIDA
GO:0001031RNA polymerase III type 2 promoter DNA bindingIDA
GO:0001032RNA polymerase III type 3 promoter DNA bindingIDA
GeneCards MAF1
PDB 3NR5
UniProt Q9H063
Vega OTTHUMG00000165244
MIM 610210
Ensembl ENSG00000179632
HGNC 24966
HPRD 14345

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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