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Sequence in raw or FASTA format:

Database:

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SLX4 SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_032444 Homo sapiens SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) (SLX4), mRNA. ORF Sequence $2477.25
Peptide Services
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Gene Symbol SLX4
Entrez Gene ID 84464
Full Name SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Synonyms BTBD12, FANCP, KIAA1784, KIAA1987, MUS312
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p13.3

Summary This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.[provided by RefSeq, Jan 2011].
Disorder

MIM: 613278

mRNA Protein Product Sequence Price Select
NM_032444, 63252862 NP_115820, 63252863 structure-specific endonuclease subunit SLX4 Full Length $3286.80
ORF Sequence $2477.25
KEGG
hsa03460Fanconi anemia pathway
Homo sapiens (human)SLX4NP_115820.2
Pan troglodytes (chimpanzee)SLX4XP_510772.2
Macaca mulatta (Rhesus monkey)SLX4XP_001094220.2
Canis lupus familiaris (dog)SLX4XP_536992.3
Bos taurus (cattle)SLX4XP_002697931.1
Mus musculus (house mouse)Slx4NP_803423.2
Rattus norvegicus (Norway rat)Slx4XP_220211.5
Gallus gallus (chicken)SLX4XP_414962.3
Danio rerio (zebrafish)LOC100538153XP_003201146.1
GeneCards SLX4
UniProt Q8IY92
MIM 613278
Ensembl ENSG00000188827
HGNC 23845
HPRD 12537

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
structure-specific endonuclease subunit SLX4
Names
structure-specific endonuclease subunit SLX4
BTB (POZ) domain containing 12
BTB/POZ domain-containing protein 12
SLX4 structure-specific endonuclease subunit homolog

Interactant

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