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B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_020981 Homo sapiens UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 (B3GALT1), mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10

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Gene Symbol B3GALT1
Entrez Gene ID 8708
Full Name UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
Synonyms MGC126594, beta3Gal-T1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q24.3

Summary This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is expressed exclusively in the brain. The encoded protein shows strict donor substrate specificity for UDP-galactose. [provided by RefSeq, Jul 2008].
Disorder

MIM: 603093

mRNA Protein Product Sequence Price Select
NM_020981, 305855079 NP_066191, 10304987 beta-1,3-galactosyltransferase 1 ORF Sequence $269.00
KEGG
hsa_M00070Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer
hsa00601Glycosphingolipid biosynthesis - lacto and neolacto series
Homo sapiens (human)B3GALT1NP_066191.1
Pan troglodytes (chimpanzee)B3GALT1NP_001009096.1
Macaca mulatta (Rhesus monkey)B3GALT1XP_001102033.1
Canis lupus familiaris (dog)B3GALT1XP_545508.2
Bos taurus (cattle)B3GALT1XP_002685372.1
Mus musculus (house mouse)B3galt1NP_064679.2
Rattus norvegicus (Norway rat)B3galt1NP_001102424.1
Gallus gallus (chicken)B3GALT1XP_426584.1
Danio rerio (zebrafish)LOC571003XP_699646.1
Drosophila melanogaster (fruit fly)CG33145NP_788328.1
Drosophila melanogaster (fruit fly)CG30036NP_725096.2
Drosophila melanogaster (fruit fly)CG30037NP_725097.2
Arabidopsis thaliana (thale cress)GALT1NP_174003.1
GeneCards B3GALT1
UniProt Q9Y5Z6
MIM 603093
Ensembl ENSG00000172318
HGNC 916
HPRD 04369

General protein information

Preferred Names
beta-1,3-galactosyltransferase 1
Names
beta-1,3-galactosyltransferase 1
beta3GalT1
beta-3-galt1
beta-1,3-GalTase 1
UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1
NP_066191.1

Interactant



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