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EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001034116 Homo sapiens eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa (EIF2B4), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_015636 Homo sapiens eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa (EIF2B4), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_172195 Homo sapiens eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa (EIF2B4), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Gene Symbol EIF2B4
Entrez Gene ID 8890
Full Name eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
Synonyms DKFZp586J0119, EIF-2B, EIF2B, EIF2Bdelta
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p23.3

Summary Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 606687

Leukoencephaly with vanishing white matter, 603896 (3);

mRNA Protein Product Sequence Price Select
NM_001034116, 78000157 NP_001029288, 78000158 translation initiation factor eIF-2B subunit delta isoform 2 ORF Sequence $550.00
NM_015636, 78000155 NP_056451, 78000156 translation initiation factor eIF-2B subunit delta isoform 3 ORF Sequence $550.00
NM_172195, 187607322 NP_751945, 187607323 translation initiation factor eIF-2B subunit delta isoform 1 ORF Sequence $550.00
KEGG
hsa03013RNA transport
WikiPathways
WP107Translation Factors
Reactome
REACT_2159Eukaryotic Translation Initiation
REACT_2099Cap-dependent Translation Initiation
REACT_1014Translation
REACT_1815Recycling of eIF2:GDP
REACT_71Gene Expression
REACT_17015Metabolism of proteins
Homo sapiens (human)EIF2B4NP_751945.2
Pan troglodytes (chimpanzee)EIF2B4XP_515356.2
Macaca mulatta (Rhesus monkey)EIF2B4XP_001094256.2
Canis lupus familiaris (dog)EIF2B4XP_860642.1
Bos taurus (cattle)EIF2B4NP_001029716.1
Mus musculus (house mouse)Eif2b4NP_001120828.1
Rattus norvegicus (Norway rat)Eif2b4NP_446402.1
Gallus gallus (chicken)EIF2B4XP_423512.2
Danio rerio (zebrafish)eif2b4NP_001014383.1
Drosophila melanogaster (fruit fly)eIF2B-deltaNP_611790.1
Caenorhabditis elegansCELE_F11A3.2NP_001023784.1
Arabidopsis thaliana (thale cress)AT1G48970NP_175327.3
Arabidopsis thaliana (thale cress)AT5G38640NP_198680.1
GeneCards EIF2B4
UniProt Q9UI10
MIM 606687
Ensembl ENSG00000115211
HGNC 3260
HPRD 09459

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
translation initiation factor eIF-2B subunit delta
Names
translation initiation factor eIF-2B subunit delta
eIF-2B GDP-GTP exchange factor subunit delta
translation initiation factor eIF-2b delta subunit
eukaryotic translation initiation factor 2B subunit 4 delta

Interactant



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