PLCZ1 phospholipase C, zeta 1 [Homo sapiens (human)]
| Gene Symbol | PLCZ1 |
| Entrez Gene ID | 89869 |
| Full Name | phospholipase C, zeta 1 |
| Synonyms | MGC149685, NYD-SP27, PLCzeta |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
12 12p12.3 |
| Summary | |
| Disorder | MIM: 608075 |
| mRNA | NM_033123, 25188200 |
| Protein | NP_149114, 25188201 |
| Product | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 |
| RefSeq Status | PROVISIONAL |
| hsa04114 | Oocyte meiosis |
| hsa00562 | Inositol phosphate metabolism |
| hsa01100 | Metabolic pathways |
| hsa04070 | Phosphatidylinositol signaling system |
| hsa04020 | Calcium signaling pathway |
| Homo sapiens (human) | PLCZ1 | NP_149114.2 |
| Pan troglodytes (chimpanzee) | PLCZ1 | XP_001160159.1 |
| Canis lupus familiaris (dog) | PLCZ1 | XP_543784.2 |
| Bos taurus (cattle) | PLCZ1 | NP_001011680.2 |
| Mus musculus (house mouse) | Plcz1 | NP_473407.2 |
| Rattus norvegicus (Norway rat) | Plcz1 | NP_001012234.1 |
| Gallus gallus (chicken) | PLCZ1 | NP_001034362.1 |
| ID | Name | Evidence |
| GO:0006816 | calcium ion transport | IEA |
| GO:0007275 | multicellular organismal development | IEA |
| GO:0007343 | egg activation | IEA |
| GO:0016042 | lipid catabolic process | IEA |
| GO:0035556 | intracellular signal transduction | IEA |
Component
| ID | Name | Evidence |
| GO:0005634 | nucleus | IEA |
| GO:0005737 | cytoplasm | IEA |
| GO:0048471 | perinuclear region of cytoplasm | IEA |
Function
| ID | Name | Evidence |
| GO:0004435 | phosphatidylinositol phospholipase C activity | IEA |
| GO:0004871 | signal transducer activity | IEA |
| GO:0005509 | calcium ion binding | IEA |
| GO:0016787 | hydrolase activity | IEA |
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