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LRSAM1 leucine rich repeat and sterile alpha motif containing 1 [Homo sapiens (human)]


RefSeq Accession Definition Sequence Price Select
NM_001005373 Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 2, mRNA. Full Length $1101.80
ORF Sequence $629.88
NM_138361 Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 1, mRNA. Full Length $1184.05
ORF Sequence $629.88
NM_001005374 Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 3, mRNA. Full Length $827.37
ORF Sequence $629.88
NM_001190723 Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 4, mRNA. Full Length $1073.45
ORF Sequence $606.39


Gene Symbol LRSAM1
Entrez Gene ID 90678
Full Name leucine rich repeat and sterile alpha motif containing 1
Synonyms FLJ31641, RIFLE, TAL
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q33.3
Summary LRSAM1 is a multifunctional RING finger protein that selectively regulates cell adhesion molecules, has ubiquitin ligase activity, and plays a role in receptor endocytosis and viral budding (Li et al., 2003 [PubMed 14635195]; Amit et al., 2004 [PubMed 15256501]).[supplied by OMIM].
Disorder

MIM: 610933
mRNA NM_001005373, 299758419
Protein NP_001005373, 53729361
Product E3 ubiquitin-protein ligase LRSAM1 isoform 1
RefSeq Status VALIDATED
mRNA NM_138361, 299758420
Protein NP_612370, 53729359
Product E3 ubiquitin-protein ligase LRSAM1 isoform 1
RefSeq Status VALIDATED
mRNA NM_001005374, 299758421
Protein NP_001005374, 53729363
Product E3 ubiquitin-protein ligase LRSAM1 isoform 1
RefSeq Status VALIDATED
mRNA NM_001190723, 299758422
Protein NP_001177652, 299758423
Product E3 ubiquitin-protein ligase LRSAM1 isoform 2
RefSeq Status VALIDATED
Homo sapiens (human)LRSAM1NP_001005373.1
Pan troglodytes (chimpanzee)LRSAM1XP_001149463.1
Canis lupus familiaris (dog)LRSAM1XP_548450.2
Bos taurus (cattle)LRSAM1NP_001068764.1
Mus musculus (house mouse)Lrsam1NP_955006.1
Rattus norvegicus (Norway rat)Lrsam1XP_231157.4
Gallus gallus (chicken)LRSAM1XP_415540.2
Danio rerio (zebrafish)lrsam1NP_001093474.1
Process
IDNameEvidence
GO:0000209protein polyubiquitinationIDA
GO:0015031protein transportIEA
GO:0030163protein catabolic processIMP
GO:0045806negative regulation of endocytosisIMP
GO:0046755non-lytic virus buddingIMP
GO:0051865protein autoubiquitinationIDA
GO:0070086ubiquitin-dependent endocytosisIDA
Component
IDNameEvidence
GO:0005576extracellular regionIEA
GO:0005737cytoplasmIDA
GO:0044425membrane partIDA
Function
IDNameEvidence
GO:0004842ubiquitin-protein ligase activityIDA
GO:0005179hormone activityIEA
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GO:0016874ligase activityIEA
GO:0046872metal ion bindingIEA
GeneCards LRSAM1
UniProt Q6UWE0
MIM 610933
Ensembl ENSG00000148356
HGNC 25135
HPRD 14325

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