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VAMP3 vesicle-associated membrane protein 3 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_004781 Homo sapiens vesicle-associated membrane protein 3 (VAMP3), mRNA. GenEZ ORF Cloning On-demand $299.00 14

*Business Day

Related Services

Gene Symbol VAMP3
Entrez Gene ID 9341
Full Name vesicle-associated membrane protein 3
Synonyms CEB
General protein information
Preferred Names
vesicle-associated membrane protein 3
Names
vesicle-associated membrane protein 3
VAMP-3
cellubrevin
synaptobrevin-3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p36.23

Summary Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].
Disorder

MIM: 603657

mRNA Protein Product Sequence Price Select
NM_004781, 42544205 NP_004772, 4759300 vesicle-associated membrane protein 3 ORF Sequence $150.00
KEGG
hsa04130SNARE interactions in vesicular transport
hsa04145Phagosome
Pathway Interaction Database
arf6_traffickingpathwayArf6 trafficking events
Homo sapiens (human)VAMP3NP_004772.1
Pan troglodytes (chimpanzee)VAMP3NP_001233512.1
Macaca mulatta (Rhesus monkey)VAMP3XP_001095950.1
Canis lupus familiaris (dog)VAMP3XP_005620536.1
Bos taurus (cattle)VAMP3NP_001039380.1
Mus musculus (house mouse)Vamp3NP_033524.1
Rattus norvegicus (Norway rat)Vamp3NP_476438.1
Gallus gallus (chicken)VAMP3NP_001034578.1
Danio rerio (zebrafish)vamp3NP_001002073.1
Xenopus (Silurana) tropicalis (western clawed frog)vamp3NP_001016972.1
Process
IDNameEvidence
GO:0001921positive regulation of receptor recyclingISS
GO:0006461protein complex assemblyIEA
GO:0006887exocytosisTAS
GO:0006904vesicle docking involved in exocytosisTAS
GO:0016192vesicle-mediated transportISS
GO:0017156calcium ion-dependent exocytosisIEA
GO:0034446substrate adhesion-dependent cell spreadingISS
GO:0042147retrograde transport, endosome to GolgiIDA
GO:0043001Golgi to plasma membrane protein transportIEA
GO:0061025membrane fusionTAS
Component
IDNameEvidence
GO:0005886plasma membraneISS
GO:0016021integral component of membraneIEA
GO:0016324apical plasma membraneIEA
GO:0030054cell junctionIEA
GO:0030136clathrin-coated vesicleIDA
GO:0030141secretory granuleIEA
GO:0030665clathrin-coated vesicle membraneIEA
GO:0031201SNARE complexIEA
GO:0043005neuron projectionIEA
GO:0045202synapseIEA
GO:0055037recycling endosomeIDA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GO:0017075syntaxin-1 bindingIEA
GeneCards VAMP3
UniProt Q6FGG2, Q15836
Vega OTTHUMG00000001225
MIM 603657
Ensembl ENSG00000049245
HGNC 12644
HPRD 04711

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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