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MAGED1 melanoma antigen family D, 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001005332 Homo sapiens melanoma antigen family D, 1 (MAGED1), transcript variant 3, mRNA. GenEZ ORF Cloning In-stock $809.00 $760.00 15
NM_001005333 Homo sapiens melanoma antigen family D, 1 (MAGED1), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $809.00 $760.00 15
NM_006986 Homo sapiens melanoma antigen family D, 1 (MAGED1), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $809.00 $760.00 15

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Related Services

Gene Symbol MAGED1
Entrez Gene ID 9500
Full Name melanoma antigen family D, 1
Synonyms DLXIN-1, NRAGE
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp11.23

Summary This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 300224

mRNA Protein Product Sequence Price Select
NM_001005332, 52632378 NP_001005332, 52632379 melanoma-associated antigen D1 isoform b ORF Sequence $660.00
NM_001005333, 52632380 NP_001005333, 52632381 melanoma-associated antigen D1 isoform a ORF Sequence $660.00
NM_006986, 52632376 NP_008917, 52632377 melanoma-associated antigen D1 isoform b ORF Sequence $660.00
KEGG
hsa04722Neurotrophin signaling pathway
Pathway Interaction Database
p75ntrpathwayp75(NTR)-mediated signaling
trkrpathwayNeurotrophic factor-mediated Trk receptor signaling
Reactome
REACT_13648Regulation of Apoptosis
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
REACT_13638NRAGE signals death through JNK
REACT_13776p75 NTR receptor-mediated signalling
REACT_578Apoptosis
REACT_13720Cell death signalling via NRAGE, NRIF and NADE
REACT_22128Role of DCC in regulating apoptosis
Homo sapiens (human)MAGED1NP_001005333.1
Pan troglodytes (chimpanzee)MAGED1XP_003317513.1
Macaca mulatta (Rhesus monkey)LOC696658XP_002808576.1
Canis lupus familiaris (dog)MAGED1XP_538044.4
Bos taurus (cattle)MAGED1NP_001039590.2
Mus musculus (house mouse)Maged1NP_062765.1
Rattus norvegicus (Norway rat)Maged1NP_445861.1
GeneCards MAGED1
UniProt Q9Y5V3
MIM 300224
Ensembl ENSG00000179222
HGNC 6813
HPRD 02202

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
melanoma-associated antigen D1
Names
melanoma-associated antigen D1
MAGE-D1 antigen
MAGE tumor antigen CCF
neurotrophin receptor-interacting MAGE homolog

Interactant



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