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Sequence in raw or FASTA format:

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ADAMTSL2 ADAMTS-like 2 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu22075 NM_001145320 Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu22075 NM_014694 Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu43613 XM_005272237 PREDICTED: Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu43614 XM_006717336 PREDICTED: Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu43615 XM_005272238 PREDICTED: Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu22075 XM_006717337 PREDICTED: Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu22075 XM_005272239 PREDICTED: Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu22075C NM_001145320 Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant 2, mRNA. Customized vector On-demand 12-14 $329.00
OHu22075C NM_014694 Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant 1, mRNA. Customized vector On-demand 12-14 $329.00
OHu43613C XM_005272237 PREDICTED: Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant X1, mRNA. Customized vector On-demand 25 $1699.00
OHu43614C XM_006717336 PREDICTED: Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant X4, mRNA. Customized vector On-demand 25 $1699.00
OHu43615C XM_005272238 PREDICTED: Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant X2, mRNA. Customized vector On-demand 12-14 $329.00
OHu22075C XM_006717337 PREDICTED: Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant X5, mRNA. Customized vector On-demand 12-14 $329.00
OHu22075C XM_005272239 PREDICTED: Homo sapiens ADAMTS-like 2 (ADAMTSL2), transcript variant X3, mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol ADAMTSL2
Entrez Gene ID 9719
Full Name ADAMTS-like 2
Synonyms GPHYSD1
General protein information
Preferred Names
ADAMTS-like protein 2
Names
ADAMTS-like protein 2
ADAMTSL-2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q34.2

Summary This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009].
Disorder

MIM: 612277

Geleophysic dysplasia, 231050 (3)

mRNA Protein Product Sequence Price Select
NM_001145320, 223718259 NP_001138792, 223718260 ADAMTS-like protein 2 precursor ORF Sequence $750.00
NM_014694, 223718256 NP_055509, 41281450 ADAMTS-like protein 2 precursor ORF Sequence $750.00
XM_005272237, 530427262 XP_005272294, 530427263 ADAMTS-like protein 2 isoform X1 ORF Sequence $1500.00
XM_005272238, 530427264 XP_005272295, 530427265 ADAMTS-like protein 2 isoform X2 ORF Sequence $750.00
XM_005272239, 530427266 XP_005272296, 530427267 ADAMTS-like protein 2 isoform X3 ORF Sequence $750.00
XM_006717336, 578818017 XP_006717399, 578818018 ADAMTS-like protein 2 isoform X4 ORF Sequence $1500.00
XM_006717337, 578818019 XP_006717400, 578818020 ADAMTS-like protein 2 isoform X5 ORF Sequence $750.00
Reactome
REACT_17015Metabolism of proteins
REACT_22161Post-translational protein modification
REACT_200727O-linked glycosylation
REACT_200626O-glycosylation of TSR domain-containing proteins
Homo sapiens (human)ADAMTSL2NP_001138792.1
Pan troglodytes (chimpanzee)ADAMTSL2XP_001169765.2
Macaca mulatta (Rhesus monkey)LOC713492XP_002808139.1
Canis lupus familiaris (dog)ADAMTSL2XP_003639356.1
Bos taurus (cattle)ADAMTSL2NP_001192863.1
Mus musculus (house mouse)Adamtsl2NP_084257.1
Rattus norvegicus (Norway rat)Adamtsl2XP_231125.3
Gallus gallus (chicken)ADAMTSL2XP_004946003.1
Danio rerio (zebrafish)adamtsl2XP_003198768.2
Xenopus (Silurana) tropicalis (western clawed frog)adamtsl2XP_004919863.1
Process
IDNameEvidence
GO:0006508proteolysisIEA
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayIMP
Component
IDNameEvidence
GO:0005578proteinaceous extracellular matrixIEA
Function
IDNameEvidence
GO:0004222metalloendopeptidase activityIEA
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GeneCards ADAMTSL2
UniProt B1B0D4, Q86TH1
Vega OTTHUMG00000131706
MIM 612277
Ensembl ENSG00000197859
HGNC 14631
HPRD 11096

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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