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MAML1 mastermind-like 1 (Drosophila) [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_014757 Homo sapiens mastermind-like 1 (Drosophila) (MAML1), mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Gene Symbol MAML1
Entrez Gene ID 9794
Full Name mastermind-like 1 (Drosophila)
Synonyms FLJ53540, KIAA0200, Mam-1, Mam1
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008].

MIM: 605424

mRNA Protein Product Sequence Price Select
NM_014757, 208022630 NP_055572, 7661990 mastermind-like protein 1 ORF Sequence $1500.00
hsa04330Notch signaling pathway
WP61Delta-Notch Signaling Pathway
WP268Notch Signaling Pathway
Pathway Interaction Database
hes_heypathwayNotch-mediated HES/HEY network
notch_pathwayNotch signaling pathway
REACT_14835Notch-HLH transcription pathway
REACT_71Gene Expression
REACT_111102Signal Transduction
REACT_118859Signaling by NOTCH1
REACT_118744Pre-NOTCH Expression and Processing
REACT_12627Generic Transcription Pathway
REACT_118568Pre-NOTCH Transcription and Translation
REACT_299Signaling by NOTCH
REACT_118780NOTCH1 Intracellular Domain Regulates Transcription
Homo sapiens (human)MAML1NP_055572.1
Pan troglodytes (chimpanzee)MAML1XP_527150.3
Macaca mulatta (Rhesus monkey)MAML1XP_001105097.2
Canis lupus familiaris (dog)MAML1XP_538578.3
Bos taurus (cattle)MAML1XP_002688543.1
Mus musculus (house mouse)Maml1NP_780543.2
Rattus norvegicus (Norway rat)Maml1NP_001100467.1
Gallus gallus (chicken)MAML1XP_414607.3
Danio rerio (zebrafish)LOC567335XP_695719.3
GeneCards MAML1
PDB 3NBN, 2F8X, 3V79
UniProt Q92585
MIM 605424
Ensembl ENSG00000161021
HGNC 13632
HPRD 05665

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
mastermind-like protein 1
mastermind-like protein 1
mastermind homolog


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